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Protein Alignment Ptp10D and Ptprf

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	XP_038966081.1	Gene:	Ptprf / 360406	RGDID:	3453	Length:	1928	Species:	Rattus norvegicus

Alignment Length:	1732	Identity:	406/1732 - (23%)
Similarity:	630/1732 - (36%)	Gaps:	550/1732 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 SIPNNPGLDDGASYRLDYSPPFGYPEPNTTIASREIGDEIQFSRALPGTKYNFWLYYTN--FTHH 110
            |.|.|..:.|....| ..:|.|..|.     :|:|:         :||...|.......  ..:.
  Rat   224 SAPANLYVRDQREVR-RVAPRFSIPP-----SSQEV---------MPGGNVNLTCVAVGAPMPYV 273

  Fly   111 DWLTWTVTITTAPDPPSNLSVQVRSGKNAIILWSPPTQGSYTAFKIKVLGLSEASSSYNRTFQVN 175
            .|:.....:|...:.|        .|:|.:.|.:.....:||...|..||:.||
  Rat   274 KWMMGAEELTKEDEMP--------VGRNVLELSNVMRSANYTCVAISSLGMIEA----------- 319

  Fly   176 DNTFQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPP 240
              |.|.:||.|                              |..|...:|.....|::.:.|
  Rat   320 --TAQVTVKAL------------------------------PKPPIDLVVTETTATSVTLTW--- 349

  Fly   241 YPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGLVPGRAYNISVQTMSEDEISLPTT 305
                            |:.::        ||     .:|.|:
  Rat   350 ----------------DSGNT--------EP-----VSFYGI----------------------- 362

  Fly   306 AQYRTV----PLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATTRRQSTVPRSNEPV 366
             |||..    |.:.:      |.:.|..:.:     .|:|.|.:|...|.........|.|..
  Rat   363 -QYRAAGTDGPFQEV------DGVASTRYSI-----GGLSPFSEYAFRVLAVNSIGRGPPSEA-- 413

  Fly   367 AFFDFRDIAEPGKTFNVIVKTVSGKVTSWPATGDVTLRPLPVRNLRSINDDKTNTMIITWE--AD 429
                            |..:|.....:|.|       |.:..|.|      ..:||::.||  .:
  Rat   414 ----------------VRARTGEQAPSSPP-------RRVQARML------SASTMLVQWEPPEE 449

  Fly   430 PASTQDEYRIVY-----------HELETFNGDTSTLTTDRTRFTLESLLPGRNYSLSVQAVSKKM 483
            |......||:.|           |:   .|.|...||      |:.|||||..|||.|.|.:.
  Rat   450 PNGLVRGYRVYYTPDSRRPLSAWHK---HNTDAGLLT------TVGSLLPGITYSLRVLAFTA-- 503

  Fly   484 ESNETSIFVVTRPSSPIIEDLKSIRMG-----------------LNISWKSDVNSKQEQYEVLYS 531
                    |...|.||.|: :|: :.|                 :.:||......:..:||::|
  Rat   504 --------VGDGPPSPTIQ-VKT-QQGVPAQPADFQAKAESDTRIQLSWLLPPQERIIKYELVY- 557

  Fly   532 RNGTSDLRTQKTK-----ESRLVIKNLQPGAGYELKVFAVSHDL--------------RSEPHAY 577
              ..::...|:.|     .|...:::|:|...|..::.|.| ||              :|.|.|
  Rat   558 --WAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARS-DLGVGVFTPTVEARTAQSTPSA- 618

  Fly   578 FQAVYPNPPRNMTIETVRSNSVLVHWSPP----ESGEFTEYSIRYR-TDSEQQWVRLPSVRSTEA 637
                   ||:.:|..:..|.:|.|.|.||    .:|..|:||:.|. .|.|.:...:....|.|.
  Rat   619 -------PPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREH 676

  Fly   638 DITDMTKGEKYTIQVNTVSFGVESPVPQEVNTTVPPNPVSNIIQLVDSRNITLEWPKPEGRVESY 702
            ...|:...||:|          |..|....:|.|.|.|.|:.:.:....::
  Rat   677 SSWDLLGLEKWT----------EYRVWVRAHTDVGPGPESSPVLVRTDEDV-------------- 717

  Fly   703 ILKWWPSDNPGRVQTKNVSENKSADDLSTVRVLIGELMPGVQYKFDIQTTSYGILSGITSLY--- 764
                 ||..|.:|:         .:.|::..|       .|.:|..:....:|.:.|....|
  Rat   718 -----PSGPPRKVE---------VEPLNSTAV-------HVSWKLPVPNKQHGQIRGYQVTYVRL 761

  Fly   765 ----PRTMPLIQSDVVVANG-----EKEDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEK 820
                ||..|:|| ||::|..     |.||...||:   ..||:::....:..::......|.|.|
  Rat   762 ENGEPRGQPIIQ-DVMLAEAQWRPEESEDYETTIS---GLTPETTYSITVAAYTTKGDGARSKPK 822

  Fly   821 LANDTDRKVTFTGLVPGRLYNITVWTVSGGVASLPIQRQDRLYPEPITQLHATNITDTEISLRWD 885
            :       ||.||.||||                           | |.:.:|....|.: |:|.
  Rat   823 V-------VTTTGAVPGR---------------------------P-TMMVSTTAMHTAL-LQWH 851

  Fly   886 LPK---GEYNDFDIAYLTADNLLAQNMTTRNE---ITISDLRPHRNYTFTVVVRS----GTESSV 940
            .||   ||...:.:.|..||......:....:   .|::.|.....|.|.:..::    |.|
  Rat   852 PPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGEE--- 913

  Fly   941 LRSSSPLSASFTTNEAVP-GRVERFHPTDVQPSEINFEWSLP-SSEANGVIRQFSIAYTNINNLT 1003
                  .....||.|..| |..:....|.:..|.....|..| .:|.||.|..:::.|.:||:
  Rat   914 ------FEKEITTPEDAPSGFPQNLRVTGLTTSTTELAWDPPVLAERNGRITNYTVVYRDINS-- 970

  Fly  1004 DAGMQDFESEEAFG----VIKNLKPGETYVFKIQAKTAIGFGP--EREYRQTMP----------- 1051
                 ..|.:...|    .:..|||..||..|::|.|:.|.||  .....||||
  Rat   971 -----QHELQNVTGDVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSQTMPMEQVFAKNFRV 1030

  Fly  1052 ------------------------------------------ILAPPRPATQVVPTEVYRSSST- 1073
                                                      ::|..:|.|:.....:.|.||.
  Rat  1031 AAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAG 1095

  Fly  1074 -----IQIRFRKNYFSD---------QNGQ-------------VRMYTIIVAEDDAKNASGLEMP 1111
                 :.||...:....         ::|:             ||.:.|:|...| :....|..|
  Rat  1096 GLQHLVSIRTAPDLLPQKPLPASAFIEDGRFSLSMPQVQDPSLVRWFYIVVVPID-RVGGNLLAP 1159

  Fly  1112 SWLDVQSYSVWLPYQAID-----------------PYYPFE-NRSVEDFTIGTENCDNHKIGYCN 1158
            .|...:...:....:||:                 ||...: :...|.||:|.:.  |:: |:.|
  Rat  1160 RWSTPEELELDELLEAIEQGEEKQRRRRRQAERLKPYVAAQVDELPETFTLGDKK--NYR-GFYN 1221

  Fly  1159 GPLKSGTTYRVKVRAF----TGADKFTDTAYS-------FPIQTDQDNTSLIVAITVPLTIILVL 1212
            .||....:|:..|.|.    ....::..:.||       .|.|..::...|.|...|...|:::|
  Rat  1222 RPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVLAVILIIL 1286

  Fly  1213 LV-TLLFYKRRRNNCRKTTKDSRANDNMSLPDSV-------IEQNR------------------- 1250
            :| .:|.:||:|.:    :..|:...::.|.||:       :|..|
  Rat  1287 IVIAILLFKRKRTH----SPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGSSAPSCPNISSM 1347

  Fly  1251 ----PILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHS 1311
                ||.|.:.|::...:.|:...:||:|:|.: ..|:......::...|:||||:.|::.||||
  Rat  1348 RDHPPIPITDLADNIERLKANDGLKFSQEYESI-DPGQQFTWENSNSEVNKPKNRYANVIAYDHS 1411

  Fly  1312 RFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEK 1376
            |..|..:|...|||||||||:.|:.....:|.|||||..|..|||||.||..:..:||:||..||
  Rat  1412 RVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEK 1476

  Fly  1377 GREKCDQYWP---NDTVPVFYGDIKVQILNDSHYADWVMTEFMLCR--GSEQRILRHFHFTTWPD 1436
            .|.|||||||   .:|    ||.|:|.:::....|.:.|..|.|.:  .||:|.||.|.|..|||
  Rat  1477 SRVKCDQYWPARGTET----YGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPD 1537

  Fly  1437 FGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVY 1501
            .|||..|..::.|:|..:.....:..|:||||||||||:|.||.:|.:|:::.....|||:|.|.
  Rat  1538 HGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVT 1602

  Fly  1502 AMRKERVWMVQTEQQYICIHQCLL-AVLEGKENIVGPAREMH 1542
            .||.:|.:|||||.||:.||:.|| |.:.|...::  ||.::
  Rat  1603 CMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVL--ARNLY 1642

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.