DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and Y71G12B.31

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_001293450.1	Gene:	Y71G12B.31 / 3565511	WormBaseID:	WBGene00044348	Length:	423	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	83/251 - (33%)
Similarity:	125/251 - (49%)	Gaps:	34/251 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1300 NRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHS-------TRDDFWR 1357
            ||:::|:||||:..:|     |.| |||||::|.|.:....:|.||||:.|       |..||||
Worm   170 NRYSDIVPYDHTLVEL-----DTG-DYINASFVQGESDATRWIATQGPIDSGECIGKETVSDFWR 228

  Fly  1358 MCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPV-FYGDIKVQILNDSHYADWVMTEFML---- 1417
            |..:.:...||||.:..|...:||.:|||:..... .||::.|:::.:.....||..||.:
Worm   229 MIVQYDVACIVMLGQHQEDFVQKCGEYWPSAMGKTERYGEVDVKLVCELEEKTWVHREFDVSPTS 293

  Fly  1418 -----------CRGSEQRI---LRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHC 1468
                       .|.|.|:.   :..:.:..|.|.|........:.|:...|.|  ....||||||
Worm   294 SYSSSTKSSRKSRASRQQSHMKVSQWQYKEWKDTGGAPRIANFLEFLLQVRGR--QYTSPIVVHC 356

  Fly  1469 SAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCL 1524
            |||:||:|.||..|.::.:..:...:|||..|...|::|..||.|.:||.||:..:
Worm   357 SAGIGRTGVFICTDNVISRFESEGIIDIFSEVNRSRQQRPSMVYTVKQYECIYDII 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	83/251 (33%)
		PTPc	1298..1525	CDD:238006	83/251 (33%)
Y71G12B.31	NP_001293450.1	PTPc	170..414	CDD:238006	83/251 (33%)
Y71G12B.31	NP_001293450.1	Y_phosphatase	170..412	CDD:278528	83/249 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910