DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and Y62F5A.10

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_001022486.1	Gene:	Y62F5A.10 / 3564988	WormBaseID:	WBGene00013388	Length:	437	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	74/291 - (25%)
Similarity:	132/291 - (45%)	Gaps:	44/291 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1296 NRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHSTRDDFWRMCW 1360
            |..||: |::.|...:.....|...|   .|:|.:.|...:.....::.|.|.....::|||..:
Worm   174 NLAKNQ-TDVYPILDATLVKDPAKPD---SYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAY 234

  Fly  1361 ESNSRAIVMLTRCFEKGREKCDQYWPNDTVP-VFYGDI-----KVQILND--SHYADWVMTEFML 1417
               :..:||:........||.| ::|..|.. ::||::     ||:.:::  |.|     |..:|
Worm   235 ---NEQVVMMYVLVGSEDEKYD-FFPKTTGSFLYYGEMFVNVRKVEKMDEERSRY-----TIEVL 290

  Fly  1418 CRGSEQRILRHFH-FTTWPDFGVP----NPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGT 1477
            ..|....::.:.: .|.|..||||    |..:::|..:...:...|:|:  ::|....|.||:|.
Worm   291 PNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEK--LLVVSKNGCGRAGF 353

  Fly  1478 FITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKENIVGPAREMH 1542
            ||||......:|.:....|..||.|:|.:|...|::.:||..::.|||..:  |:.|..|
Worm   354 FITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYI--KKKITVP----- 411

  Fly  1543 DNEGYEGQQVQLDENGDVVATIEGHLSHHDL 1573
                 ||.|.:::   |:...:|| ::..||
Worm   412 -----EGLQQKVE---DLKRGLEG-ITREDL 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	61/241 (25%)
		PTPc	1298..1525	CDD:238006	60/239 (25%)
Y62F5A.10	NP_001022486.1	PTPc	162..402	CDD:214550	62/242 (26%)
Y62F5A.10	NP_001022486.1	PTPc	177..402	CDD:304379	61/239 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910