DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptp10D and ptprn2

DIOPT Version :9

Sequence 1:NP_996413.2 Gene:Ptp10D / 32115 FlyBaseID:FBgn0004370 Length:1990 Species:Drosophila melanogaster
Sequence 2:NP_001122139.1 Gene:ptprn2 / 325033 ZFINID:ZDB-GENE-030131-3758 Length:1027 Species:Danio rerio


Alignment Length:1171 Identity:243/1171 - (20%)
Similarity:418/1171 - (35%) Gaps:339/1171 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   486 NETSIFVVTRPSSPIIEDLKSIRMGL---NISWKSDVNSKQEQYEVL---------------YSR 532
            ::.|.|.|   |...::.|:|:...|   ..:|:.|:..:....|:.               :..
Zfish    58 SDVSSFDV---SPAAVQRLRSVLQKLAHRGYTWQDDITQQVISKELSQLPRVSLGGFANTFPHFN 119

  Fly   533 NGTSDLRTQKTKESRLVIKNLQPGAGYELKVFAVSHDLRSEPHAYFQAVYPNPPRNMTIET-VRS 596
            :.:..|:.||...||.:.:.||   |:          |.|:..::.|:  |...|....|. :|:
Zfish   120 DNSRKLKAQKEAASRTLQRFLQ---GF----------LPSDVSSFKQS--PQGRREFWKENGLRN 169

  Fly   597 NSVLVHWSPPESGEFTEYSIRYRTDSEQQWVRLPSVRST----EADITDMTKGEKYTIQVNTVSF 657
            :.|.:.   |.|.:..  .::.|.|.:....:|||.||:    |.|.:.:...|....|...   
Zfish   170 HKVFIQ---PPSAQIP--FLQGRPDLQTTVAQLPSGRSSFSGFEQDRSGVPLAELQQYQAGP--- 226

  Fly   658 GVESPVPQEVNT-------TVPPNPVSNIIQLVDSRNITLEWPKPEGRVESYILKWWPSDNPGRV 715
             :.:..|.:..|       ::...|.:.|.:|..:   :.:.|||:  :|..:|| ..:.:|.|.
Zfish   227 -MRAQDPGKGQTQGKLHYFSLQRTPATKIEKLPGA---SRQPPKPQ--IEKLLLK-SSASSPARK 284

  Fly   716 QTKNVSENKSADDLSTVRVLIGELMPGVQYKFDIQTTSYGILSGITSLYPRTMP-----LIQSDV 775
            :..:..:.|..|              ||..:...|:.:      :.:|.|:.:.     :.|:..
Zfish   285 EALSTVDEKFID--------------GVVNQLGRQSVN------VDTLTPKDLDKLSKVITQALR 329

  Fly   776 VVANGEKEDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGLVPGRLY 840
            ||...||...||.                    :.|:.|::                        
Zfish   330 VVDGEEKVKGRDA--------------------TQGEIEVK------------------------ 350

  Fly   841 NITVWTVSGGVASLPIQRQDRLYPEPITQLH---------ATNITDTEISLRWDLPKGEYNDFDI 896
                                   .||..:||         ...:|.||.:..    |.|  |.|.
Zfish   351 -----------------------REPSQELHQMEKAEDGPTHKVTQTEETAH----KSE--DKDK 386

  Fly   897 AYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVVVRSGTESSVLRSSSPLSASFTTNEAVPGRV 961
            .:::  .||  ....||..|.|...|..  :|...:......|.||:|.....|.||...|....
Zfish   387 GFIS--QLL--EFLDRNSGTESAHPPQE--SFLGYINQPNAGSPLRASLENVQSRTTQREVDLMK 445

  Fly   962 ERFHP--TDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKP 1024
            ::..|  .||:|.:...|..:.|||.:..:                                   
Zfish   446 KKMEPDTLDVEPVDAEVEQWMHSSEGSPQV----------------------------------- 475

  Fly  1025 GETYVFKIQAKTAIGFGPEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQ 1089
                  |.:|:|     .:...:|:|.            ..||.:....:::.. ..|.|..:|.
Zfish   476 ------KAEAQT-----DKEPQKQSMD------------KEEVEKKGVRVEVNI-ATYSSPHDGD 516

  Fly  1090 VRMYTIIVAEDDAKNASGLEMPSWLDVQSYSV------WLPYQAIDPYYPFENRSVEDFTIGTEN 1148
               :..|:.||......||.:   :::.:..|      :|....:.|...|..|.      ...|
Zfish   517 ---FGYIITEDSLSTDQGLNL---MEILAERVRLHVTDFLQLSVLGPAVTFRLRP------NARN 569

  Fly  1149 CDNHKIGYC----NGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTII 1209
            ....::...    .|.|:..:..|:.....:...|..........|.:..|..::|.:::...::
Zfish   570 ISTAQLARVAVEQKGQLEKESGLRILEAGLSDRGKLNHIPLVKQSQVEPGNFLILVVVSMVFIVL 634

  Fly  1210 LVLLVTLLFYKRRRNN-------------------------CRK-----------------TTKD 1232
            ::.:...|:..|.|::                         ||:                 .:..
Zfish   635 VLGMSGALYCLRHRSHHKLKEKLAGLGNDTGHDATAAYQDLCRQRMAVQTSERGERSEVFHPSHT 699

  Fly  1233 SRAN------------------DNMSLPDSVIEQNRPI----LIKNFAEHYRLMSADSDFRFSEE 1275
            ||.|                  ...|..:...:.|..|    :|.::.|.: |.:.|   |..:|
Zfish   700 SRINSVSSQFSDGPMQSPSARSSTSSWSEEPSQTNMDISTGHMILSYMEDH-LQNKD---RLDKE 760

  Fly  1276 FEEL-KHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPR 1339
            :|.| .:......|.......|..:||...:|.||||||.|:..::...||||||:.:..|: ||
Zfish   761 WEALCSYQAEPAVCAVGQEEQNVQRNRPHGVLVYDHSRFILKLENNQSRSDYINASPIMDHD-PR 824

  Fly  1340 E--FIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQIL 1402
            .  :|..||||.||..|||:|.|||....|||||...|.|.::|.||||::...: |...:|.::
Zfish   825 NPAYISAQGPLPSTVADFWQMVWESGCVVIVMLTPLAENGLKQCHQYWPDEGSDL-YHIYEVNLV 888

  Fly  1403 NDSHYA-DWVMTEFML--CRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPI 1464
            ::..:. |:::..|.|  .:.:|.|.:..|||.:|.|..||...:||:.|.|...........||
Zfish   889 SEHIWCDDFLVRSFYLKNVQTNETRTVTQFHFLSWMDQNVPESARTLLDFRRKVNKCYRGRSCPI 953

  Fly  1465 VVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVL 1528
            :||||.|.|||||:|.:|.:|.:: ..:..:||...:..:|.:|..||||:.|:   ...|.||.
Zfish   954 IVHCSDGAGRSGTYILIDMVLNKMAKGAKEIDIAATLEHLRDQRSGMVQTKDQF---EFALTAVA 1015

  Fly  1529 E 1529
            |
Zfish  1016 E 1016

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ptp10DNP_996413.2 fn3 124..205 CDD:278470
fn3 220..304 CDD:278470
fn3 315..391 CDD:278470
FN3 405..494 CDD:238020 2/7 (29%)
FN3 511..574 CDD:238020 14/80 (18%)
FN3 583..671 CDD:238020 20/99 (20%)
fn3 683..753 CDD:278470 13/69 (19%)
fn3 787..850 CDD:278470 3/62 (5%)
fn3 866..935 CDD:278470 18/77 (23%)
fn3 961..1043 CDD:278470 11/83 (13%)
PTPc 1272..1525 CDD:214550 92/259 (36%)
PTPc 1298..1525 CDD:238006 87/232 (38%)
ptprn2NP_001122139.1 RESP18 50..>105 CDD:291609 10/49 (20%)
Receptor_IA-2 518..602 CDD:288410 14/92 (15%)
PTPc 757..1016 CDD:214550 95/263 (36%)
PTPc 785..1016 CDD:238006 90/235 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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