Protein Alignment Ptp10D and Ptpn7

DIOPT Version :9

• Sequence 1: NP_996413.2
• Gene: Ptp10D / 32115
• FlyBaseID: FBgn0004370
• Length: 1990
• Species: Drosophila melanogaster
• Sequence 2: NP_001343311.1
• Gene: Ptpn7 / 320139
• MGIID: 2156893
• Length: 359
• Species: Mus musculus
• Alignment Length: 261
• Identity: 95/261 - (36%)
• Similarity: 136/261 - (52%)
• Gaps: 17/261 - (6%)

  Fly  1271 RFSEEFEELKHVGRDQPCTFA-----DLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINAN 1330
            :..|||.::       |..|.     |:|.:..|:|:..|||...||..|......|.|||||||
Mouse    96 QLEEEFLKI-------PSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDSDYINAN 153

  Fly  1331 YVPGHNSPRE-FIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFY 1394
            |:.|::...: :|.||||:.:|..|||.|.|:.:...|||||: ..:|:|||..|||  |....|
Mouse   154 YIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQ-LREGKEKCVHYWP--TEEEAY 215

  Fly  1395 GDIKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFR-DRIG 1458
            |..:::|.:...:.::.:.:..:....|.|.::|..|:.|||...|.....|:|.|.... ....
Mouse   216 GPFQIRIQDMKEHPEYTVRQLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVETPETA 280

  Fly  1459 AEQRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQC 1523
            |...|||||||||:||:|.||......||:.....|||.|||..:|.:|..|:||.:||..:|..
Mouse   281 ANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT 345

  Fly  1524 L 1524
            |
Mouse   346 L 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	95/260 (37%)
		PTPc	1298..1525	CDD:238006	88/229 (38%)
Ptpn7	NP_001343311.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		Interaction with MAP kinases. /evidence=ECO:0000250	38..51
		PTPc-N7	105..349	CDD:350460	92/245 (38%)
		Substrate binding. /evidence=ECO:0000250	290..296		4/5 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910