Protein Alignment Ptp10D and Ptpn20

DIOPT Version :9

• Sequence 1: NP_996413.2
• Gene: Ptp10D / 32115
• FlyBaseID: FBgn0004370
• Length: 1990
• Species: Drosophila melanogaster
• Sequence 2: NP_001073618.1
• Gene: Ptpn20 / 306281
• RGDID: 1309812
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 584
• Identity: 146/584 - (25%)
• Similarity: 223/584 - (38%)
• Gaps: 184/584 - (31%)

  Fly   958 PGRVERFHPTDVQPSE-----INFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFG 1017
            ||.|.:.|..|....|     :|.:.|||||.
  Rat     4 PGNVRQKHGRDNDEHEGDSDDLNLQKSLPSSS--------------------------------- 35

  Fly  1018 VIKNLKPGETYVFKIQAKTAIGFGPEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRKNY 1082
                           |.||           .|.|:..      ..|.:|..::|..:.
  Rat    36 ---------------QQKT-----------PTKPVFG------NKVNSESVKTSHHMS------- 61

  Fly  1083 FSDQNGQVRMYTIIVAED-DAKNASGLEMPSWLDVQSYSVWLPYQAIDPYYPFENRSVEDFTIGT 1146
            ||::      |.::..|. ::.|...|    | ||:..|....:.::||
  Rat    62 FSNK------YDLVFPEPVESDNDETL----W-DVRDLSHRNRWSSVDP---------------- 99

  Fly  1147 ENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILV 1211
            |:.         ||.|:.:|..        ::..||||.|     :::.|.            |.
  Rat   100 ESA---------GPSKTVSTVL--------SESSTDTAVS-----ERELTQ------------LA 130

  Fly  1212 LLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEF 1276
            .:..|:|....|...|...|..:..:.:.            :|:.|.|...::..| ||:...|.
  Rat   131 QIRPLIFNSSSRAALRDCLKALQKKEELD------------IIREFLELEEMIPPD-DFKSGYEL 182

  Fly  1277 EELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANY--VPGHNSPR 1339
            :                  ||.|||:.:|||||.:|..|     .:..|||||:|  :..|....
  Rat   183 Q------------------NRDKNRYRDILPYDSTRVPL-----GKNKDYINASYIRIVNHEEEY 224

  Fly  1340 EFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-NDTVPVFYGDIKVQILN 1403
            .:|.|||||..|.:|||:|..|:|...|.|:||..|.|..||..||| :...|:.:....|.:.|
  Rat   225 FYIATQGPLPDTIEDFWQMVLENNCNVIAMITREIEGGVIKCCSYWPVSLKEPLEFKHFHVLLEN 289

  Fly  1404 DSHYADWVMTEFMLCRGS--EQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFR-DRIGAEQRPIV 1465
            ......:|:..|.:.:.|  :...::|..|..|||.|.|......:::||..| ..|..   |::
  Rat   290 FQITQYFVIRIFQIVKKSTGKSHSVKHLQFIKWPDHGTPASADFFIKYVRYVRKSHITG---PLL 351

  Fly  1466 VHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLE 1529
            |||||||||:|.||.:|.:...|..:...:|..||..|||:|..|:||::||...::.:|.||:
  Rat   352 VHCSAGVGRTGVFICVDVVFCTIEKNYSFNIMNIVTQMRKQRFGMIQTKEQYQFCYEIVLEVLQ 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470	13/86 (15%)
		PTPc	1272..1525	CDD:214550	88/258 (34%)
		PTPc	1298..1525	CDD:238006	85/232 (37%)
Ptpn20	NP_001073618.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		19/118 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..116		7/55 (13%)
		PTPc	160..412	CDD:214550	94/278 (34%)
		PTPc	186..412	CDD:238006	85/233 (36%)
		Substrate binding. /evidence=ECO:0000250	354..360		5/5 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910