| Sequence 1: | NP_996413.2 | Gene: | Ptp10D / 32115 | FlyBaseID: | FBgn0004370 | Length: | 1990 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_057051.3 | Gene: | PTPN22 / 26191 | HGNCID: | 9652 | Length: | 807 | Species: | Homo sapiens |
| Alignment Length: | 756 | Identity: | 181/756 - (23%) |
|---|---|---|---|
| Similarity: | 302/756 - (39%) | Gaps: | 167/756 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1272 FSEEFEELKH------VGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINAN 1330
Fly 1331 YVPGHNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYW--PNDTVPVF 1393
Fly 1394 YGDIKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVP---NPPQTLVRFVRAFRD 1455
Fly 1456 RIGAEQRPIVVHCSAGVGRSGTFITLD---RILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQY 1517
Fly 1518 ICIHQCLLAVLEGKENIVGPAREMHDNEGYEGQQVQLDENGDVVA----------TIEG------ 1566
Fly 1567 --------HLSHHDLQQAEAEAIDDENAAILHD-------DQQPLTSSF--TGHHTHMPPTTSMS 1614
Fly 1615 SFGGGGGGHTNVDAPD------RXHSVVNQSDN--NNSVVIVLVDNKPSSMICK------DSKGG 1665
Fly 1666 NIDVLESQQQQQQQQQQQPNQGGHNITTISAINGYNTLQHRRKSQLITFSSSSCDIKNSL----S 1726
Fly 1727 HEYINGSN----GSAANG-----PPSSGSGSGSGPGSNRASRANVRLSFAEEDVMILPQN----- 1777
Fly 1778 ----HSQQSNHQDDEVF--TRRRSLLEVEIGVEVGE---DGELAPHEMEEDLEEEDEDEELYMHD 1833
Fly 1834 --EFETHIDTKSNNA-------NDDSGGGS----YEDSHALHSSLGGSNRN-------------- 1871
Fly 1872 -----SLEK----DDDDIEVDVISTDVSCYDQLLGSSCNTR 1903 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ptp10D | NP_996413.2 | fn3 | 124..205 | CDD:278470 | |
| fn3 | 220..304 | CDD:278470 | |||
| fn3 | 315..391 | CDD:278470 | |||
| FN3 | 405..494 | CDD:238020 | |||
| FN3 | 511..574 | CDD:238020 | |||
| FN3 | 583..671 | CDD:238020 | |||
| fn3 | 683..753 | CDD:278470 | |||
| fn3 | 787..850 | CDD:278470 | |||
| fn3 | 866..935 | CDD:278470 | |||
| fn3 | 961..1043 | CDD:278470 | |||
| PTPc | 1272..1525 | CDD:214550 | 93/266 (35%) | ||
| PTPc | 1298..1525 | CDD:238006 | 83/234 (35%) | ||
| PTPN22 | NP_057051.3 | PTPc | 24..288 | CDD:214550 | 93/267 (35%) |
| PTPc | 56..288 | CDD:238006 | 83/235 (35%) | ||
| Substrate binding | 227..233 | 4/5 (80%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 676..700 | 1/23 (4%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 724..746 | 2/13 (15%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||