DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and ZK809.1

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_502200.1	Gene:	ZK809.1 / 191427	WormBaseID:	WBGene00014085	Length:	428	Species:	Caenorhabditis elegans

Alignment Length:	398	Identity:	89/398 - (22%)
Similarity:	148/398 - (37%)	Gaps:	100/398 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1159 GPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRR 1223
            |..|:....:|..:|....||...|..:                |||:|:...:|.....|.|
Worm    52 GKTKNVVAKKVPSKASVIVDKKASTTET----------------TVPITVKKSMLSISTAYDR-- 98

  Fly  1224 NNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSE-EFEELK-HVGRDQ 1286
                 |..:.:            |:.:|    ...|..:....|:..:|.| .|.:.: .|.||
Worm    99 -----TVTEEK------------EKEKP----KKKEKEKWSGEDASIKFKELRFNQSEGGVRRD- 141

  Fly  1287 PCTFADLPCNRPK--------NRFTNILPYDHSRFKLQPVDDDEGSDYINAN--YVPGHNSPREF 1341
              |.|..| ||.|        ||.|:...|||:|..:|...|    ||||.:  .|| |.:|..:
Worm   142 --TEASCP-NRCKMWQSHSSRNRHTDYKCYDHNRIIVQMCKD----DYINGSKINVP-HFTPSIY 198

  Fly  1342 IVTQGPLHSTR--DDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGD------IK 1398
            :|....:.|..  ::|||:.:....:.:.::.|..|......|:.:..::....|.:      .|
Worm   199 LVQLPKMDSVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRK 263

  Fly  1399 VQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTW--PDFGVPNPPQTLVRFVRAFRDRIGAEQ 1461
            |: ..::..||..:.| :|..|....::...:..|:  |.||               .||.||:.
Worm   264 VE-KKENAKADMFVVE-LLPEGCSNAVMCSVYLHTYWKPLFG---------------PDRFGAQI 311

  Fly  1462 R-------------PIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQT 1513
            |             |.|:....|.||:...:||..:..|:.......|..||..:|::|...|.:
Worm   312 RAAHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDS 376

  Fly  1514 EQQYICIH 1521
            ..||:.::
Worm   377 YIQYVSLY 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	70/285 (25%)
		PTPc	1298..1525	CDD:238006	59/257 (23%)
ZK809.1	NP_502200.1	PTPc	146..386	CDD:214550	62/262 (24%)
ZK809.1	NP_502200.1	PTPc	159..386	CDD:304379	58/248 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910