DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and ZK484.7

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_491758.1	Gene:	ZK484.7 / 191327	WormBaseID:	WBGene00022753	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	98/341 - (28%)
Similarity:	153/341 - (44%)	Gaps:	67/341 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1220 KRRRNNCRKTTKDSRANDNMSLPDSVIEQNRP------ILIKNFAE--------HYRLMSADSDF 1270
            |||   .:|:|:.|:.....::.:....:.:.      ..:||..|        .:..|...:||
Worm     7 KRR---TKKSTQKSKEVSQRTVDEGTTAEKKTHRKQIVKFVKNALEKGPAGLRAEFAAMKRFNDF 68

  Fly  1271 RFSEEFEELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGH 1335
            ...:.|:|.:..|               |||:.::...||:|.||.|   ....|||:||:|...
Worm    69 EKMKAFKEAQEHG---------------KNRYKDVGCLDHNRVKLHP---PWPHDYIHANFVSTP 115

  Fly  1336 NSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVF------- 1393
            ::||.||.||.||..:..|||.||.:....:|.||....|||.:||..|:.....||.
Worm   116 SNPRRFICTQAPLDKSCADFWYMCLQEKVDSIFMLCNIMEKGAKKCCDYFACKDKPVLEFEEKGH 180

  Fly  1394 --------YGDIKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFV 1450
                    .|.:|.:...|:...:.|.|  :...|...:.:..:|:..|||.|||.....:|..:
Worm   181 KIIVKFESTGKMKFEKNTDAKITETVFT--VEGPGGLAQKVTQYHWIDWPDRGVPTADMAIVELL 243

  Fly  1451 RAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRIL------QQINTSDYVDIFGIVYAMRKERVW 1509
            ...|...|    |.|||||||:||:|:.:.::.||      |||..:|     .|:..:|::|..
Worm   244 AKTRPSKG----PTVVHCSAGIGRTGSVVMIEYILDQLLGGQQIEETD-----KILQKIREQRNN 299

  Fly  1510 MVQTEQQYICIHQCLL 1525
            .:||:|||:.:||.:|
Worm   300 SIQTDQQYLFVHQVIL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	85/273 (31%)
		PTPc	1298..1525	CDD:238006	82/247 (33%)
ZK484.7	NP_491758.1	Y_phosphatase	80..316	CDD:278528	84/265 (32%)
ZK484.7	NP_491758.1	PTPc	81..316	CDD:238006	84/264 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910