DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and Y39A3A.4

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_001370800.1	Gene:	Y39A3A.4 / 189720	WormBaseID:	WBGene00021435	Length:	265	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	80/287 - (27%)
Similarity:	123/287 - (42%)	Gaps:	68/287 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1223 RNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEE----------FE 1277
            :|...|...:.:..:|..:..|..|:          :|.:.:.|..:|.||.|          :.
Worm     3 KNFGNKKKNEKKGENNKDVTGSETEE----------DHLQYLKALENFIFSTEKLGIDGLVKQYR 57

  Fly  1278 ELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFI 1342
            :| ...:|...|:........|||:.:::..|:||.||: :|.....|||:||||..:.....||
Worm    58 KL-DAKQDPSLTYDAYTKYMHKNRYCDVVCLDNSRVKLK-IDKSRHGDYIHANYVKTNYLRSTFI 120

  Fly  1343 VTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHY 1407
            .:||||..|..|||||.::..:.:|::|.:.   |||...:|||:..|...||.|:|...::|
Worm   121 CSQGPLQHTIIDFWRMIFQERAESILLLCKV---GREGRPRYWPSLGVTETYGCIRVTNFSES-- 180

  Fly  1408 ADWVMTEFMLC--------------------RGSEQRILRHFHFTTWPDFGVPNP-----PQTLV 1447
                ..||.:|                    .|....:::   :..|||.|||:.     ||.|:
Worm   181 ----SEEFEICNLAVTFVPDNVPVDEQPANLEGLRVSLIK---WPNWPDCGVPDEKCHTVPQRLL 238

  Fly  1448 RFVRAFRDRIGAEQRPIVVHCSAGVGR 1474
            ..||         ..|.|||||||..|
Worm   239 AQVR---------HGPCVVHCSAGKDR 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	72/238 (30%)
		PTPc	1298..1525	CDD:238006	66/202 (33%)
Y39A3A.4	NP_001370800.1	PTPc	51..>256	CDD:214550	68/227 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910