DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and C46A5.1

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_501277.1	Gene:	C46A5.1 / 183497	WormBaseID:	WBGene00016698	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	304	Identity:	69/304 - (22%)
Similarity:	127/304 - (41%)	Gaps:	62/304 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1275 EFEELK-----HVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPG 1334
            |||::.     |:.::.      ...|..||||.:::..||||.||      ..|.||:||:| .
Worm   223 EFEKVSGYLPPHISKNH------FVSNMDKNRFVDVICMDHSRVKL------TDSSYIHANWV-D 274

  Fly  1335 HNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVP-------- 1391
            .||.::.|:||.||..|..|||:|..:...:.::::....|     .:::..|...|
Worm   275 LNSSKKAILTQLPLSHTASDFWQMIIDQKIKCVLLIMTDGE-----FNKFGGNSVFPQNQDFLKF 334

  Fly  1392 ----VFYGDIKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVR---F 1449
                :..|:.|...|...    |.:....:..|:.:..:...|:..||...:|:..:.:.:   :
Worm   335 EDRFIRVGEFKQVELGKG----WNLKVLSVSNGTYKTFIHVHHYKNWPHGSIPSDVKQIWQVQSY 395

  Fly  1450 VRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQT 1513
            :|.:.|     ..|.|....:|.||:|||...:.....: |....:::...:..:|..|:..||.
Worm   396 LRKYTD-----GHPPVYMSMSGCGRAGTFALFETAHMSLHNEQPSLNMVKCLENVRNGRLHSVQN 455

  Fly  1514 EQQYICIHQCLLAVLEGKENIVGPAREMHDNEGYEGQQVQLDEN 1557
            ..|:..:: .|:|     |:::|        .|...:.|:..||
Worm   456 LSQFSVVY-TLIA-----EHVLG--------NGIGKKDVEEQEN 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	61/270 (23%)
		PTPc	1298..1525	CDD:238006	56/242 (23%)
C46A5.1	NP_501277.1	Y_phosphatase	243..468	CDD:278528	59/251 (24%)
C46A5.1	NP_501277.1	PTPc	245..468	CDD:238006	58/249 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910