DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptp10D and C15H7.3

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_499135.1	Gene:	C15H7.3 / 182639	WormBaseID:	WBGene00007610	Length:	398	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	49/212 - (23%)
Similarity:	83/212 - (39%)	Gaps:	41/212 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1332 VPGHNSPREFIVTQGP-LHSTRD--DFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVF 1393
            ||..|  |..|:||.| |.|..|  |||||..:.:..::|:.....|...::        .:|:.
Worm   184 VPDFN--RTMILTQVPDLSSAPDIADFWRMIHQESIASVVIAVMPLEVTLQQ--------ILPLL 238

  Fly  1394 YGDIKV---QILNDSHYADWV-MTEFML------CRGSEQRILRHFHFTTWPDFGVPNPPQTLVR 1448
            .|....   ..:|:......| |||:.|      |..|....:.|.|  .|..          .|
Worm   239 SGTYSTYGKMFVNNKKVESAVGMTEYCLEIFPDGCSNSLLTTVYHLH--NWRQ----------KR 291

  Fly  1449 FVRAFRDRIGAEQRPIVVHCSA------GVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKER 1507
            .:....|.:...::.:.|:.:.      |.||:||.:||...:.|:.....|:....:.::|.||
Worm   292 GLEVVTDLVATMEKVMKVNDNTVLMSMNGTGRAGTMLTLFTAMLQVQKGKEVNAKETLASLRAER 356

  Fly  1508 VWMVQTEQQYICIHQCL 1524
            ..:|....|:..:|:.:
Worm   357 CGIVDNIDQFGTVHRSM 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	49/212 (23%)
		PTPc	1298..1525	CDD:238006	49/212 (23%)
C15H7.3	NP_499135.1	PTPc	131..374	CDD:214550	49/212 (23%)
C15H7.3	NP_499135.1	PTPc	148..374	CDD:304379	49/212 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910