Protein Alignment Ptp10D and ptpn-22

DIOPT Version :9

• Sequence 1: NP_996413.2
• Gene: Ptp10D / 32115
• FlyBaseID: FBgn0004370
• Length: 1990
• Species: Drosophila melanogaster
• Sequence 2: NP_500128.2
• Gene: ptpn-22 / 176981
• WormBaseID: WBGene00021507
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 418
• Identity: 112/418 - (26%)
• Similarity: 187/418 - (44%)
• Gaps: 78/418 - (18%)

  Fly  1230 TKDSRANDNMSLPDSVIEQNRPI---LIKNFAEH-------------YRLMSADSDFRFSEEFEE 1278
            :::.||...:...:.||.:..|.   |::.|.:.             |::.......|...|:.
 Worm    54 SEEERAATTVPNGNPVIFEKNPAMDGLLREFLKEEEAYTPQDYLRRFYQIRVEQEKLRMEAEYR- 117

  Fly  1279 LKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIV 1343
                   ..|..|  |.:..:||:.:|||||.:|.::|. |.:....|:||:.:.......|||.
 Worm   118 -------SECAVA--PQHYARNRYRDILPYDKNRVEIQK-DSENPEGYMNASLIQLPGGKTEFIA 172

  Fly  1344 TQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDT-VPVFYGDIKV-----QIL 1402
            .|.||.:|.|::|:|..|.....:|:|.:..|..:.||::|||... ....:||.::     ::.
 Worm   173 AQAPLPATLDEWWKMIDEHRVSLVVILCKLVELNKIKCERYWPEQVGESELFGDYEITLEEEKLF 237

  Fly  1403 NDSHYADWVMTEFMLCRGSEQ------RILRHFHFTTWPDFGVPNPPQTLVRFV---RAFRDRIG 1458
            :|..|       .|.|...|.      |.:...|:..|||.|.|:..:.|:..:   ....:.:.
 Worm   238 DDDEY-------LMRCLKMENQTTGECRKVHQLHYREWPDHGCPSGEKQLLNMIDLMENIHEEVS 295

  Fly  1459 -AEQRPIVVHCSAGVGRSGTFITLDRILQQI--NTSDYVDIFGIVYAMRKERVWMVQTEQQYICI 1520
             .:..||:|||||||||:||.|.::.|.:|:  .|...:||||:|..:||:|..||||:.|:..:
 Worm   296 PQDSSPILVHCSAGVGRTGTIIAINFIREQMKAETLHSIDIFGLVMTLRKQRASMVQTQDQFQFV 360

  Fly  1521 HQCLLA--------VLEGKENIVGPAREMHDNEGYEGQQVQL--------DENGDVVATIEGH-- 1567
            |:|:.:        :.|.|.::..|........|..| .|:|        ..:.|..|||..:
 Worm   361 HRCIASYCRRHLGIIEEPKLDLAPPVATADLPVGSSG-SVRLIAPPTPTTGPSTDQTATIANYNQ 424

  Fly  1568 LSHHDLQQAEAEAIDD----ENAAILHD 1591
            |.||   |:.:..:|:    |.||.:.|
 Worm   425 LHHH---QSSSNHMDEDTSTEEAASVPD 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	83/270 (31%)
		PTPc	1298..1525	CDD:238006	79/244 (32%)
ptpn-22	NP_500128.2	PTPc	102..365	CDD:214550	84/280 (30%)
		PTPc	129..365	CDD:238006	79/243 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001181
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910