DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and B0280.11

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_498560.2	Gene:	B0280.11 / 175997	WormBaseID:	WBGene00015106	Length:	441	Species:	Caenorhabditis elegans

Alignment Length:	444	Identity:	89/444 - (20%)
Similarity:	152/444 - (34%)	Gaps:	133/444 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1177 ADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRK---TTKDSR--AN 1236
            ||||.....|....|.::.||.|                   .||:..:..|   ||.:|.  :.
Worm    15 ADKFKKKKRSRSAPTSKERTSEI-------------------SKRKSRSPSKSKVTTGNSHGAST 60

  Fly  1237 DNMSLPDSVIEQNR-PILIKNFAE---------------------HYRLMSADSDFRFS------ 1273
            ||.:..|:    || .:..|.|.:                     ...|..|:|....|
Worm    61 DNKTKTDT----NRMEVTAKGFKKAKDAKKLEKKKEETGPSKTPSTIALRRAESQMELSGNRKNV 121

  Fly  1274 --------EEFEELKHVGRDQPCTF-------ADL-PCNRPKNRF-----TNILPYDHSRFKLQP 1317
                    |:.|:|..:.:.....|       .|| .|...|...     .|:..||.:|.|
Worm   122 EKGVKTWVEQLEKLVEIRKLLEADFKPIDTMKVDLEKCQAFKKNIDYCQSENVELYDANRVK--- 183

  Fly  1318 VDDDEGSDYINANY--VPGHNSPREFIVTQGPL----HSTRDDFWRMCWESNSRAIVMLTRCFEK 1376
             ...|...:.:|..  :|. .|.:..|:.|.||    ||. :.||.|......:.:.:|....|.
Worm   184 -GGGEADFFYHATVTSIPS-ISTKSTILAQLPLSDSPHSL-ESFWLMVAAQKIQRLFILIGEDEL 245

  Fly  1377 GREKCDQYWPND-----TVPV----------------FYGDIKVQILNDSHYADWVMTEFMLCRG 1420
            .:....:|:|.|     |:.|                .|.::   :..|...|.:.|.|  :|
Worm   246 DKAALSEYFPEDFKEFKTIRVNNRKTVSKSDEQPNTQLYYEV---VPKDCAEAPFAMIE--IC-- 303

  Fly  1421 SEQRILRHFHFTTWPDFGVPNPPQTLVRFVRA--FRDRIGAEQRPIVVHCSAGVGRSGTFITLDR 1483
                       ..|||..:|......:....|  |...|.::....:| .:.|.||:|:|:...:
Worm   304 -----------DFWPDGKIPTVSYGRIAATAASVFDSDIDSDATCAIV-SNYGAGRAGSFLVGVQ 356

  Fly  1484 ILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKENIVGP 1537
            .::::...|..:|..|..::|.:|...::|..||:..:  ::|:..|.:::..|
Worm   357 AIEKLQAGDAPNIKEIAMSIRSQRPCAIETLPQYVFTY--IIALTYGLKHVKDP 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	61/308 (20%)
		PTPc	1298..1525	CDD:238006	53/260 (20%)
B0280.11	NP_498560.2	PTPc	141..398	CDD:214550	57/283 (20%)
B0280.11	NP_498560.2	PTPc	177..394	CDD:304379	51/241 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910