DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and Y54F10BM.3

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_001368044.1	Gene:	Y54F10BM.3 / 175350	WormBaseID:	WBGene00021858	Length:	622	Species:	Caenorhabditis elegans

Alignment Length:	300	Identity:	75/300 - (25%)
Similarity:	117/300 - (39%)	Gaps:	86/300 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1275 EFE---ELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYV--PG 1334
            |||   ||..:....|..     |..||     :..:|.:.:.   |||   :.:|:|:.|  ||
Worm   264 EFEIPIELTAMSAGNPKL-----CRDPK-----VQAWDSTSYL---VDD---THFIHASTVTAPG 312

  Fly  1335 HNSPREFIVTQGPLH-------STRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDT-VP 1391
            .....:.|:.|.|..       .||:.||||.|::.:..:||..:..|.|.:||.:|:|::| ..
Worm   313 KEYIGKAIICQAPFDDKEKGHPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGAT 377

  Fly  1392 VFYGDIKVQILNDSHYADWVMTEFMLCRGSEQ--------------RILRHFHFTTWPD------ 1436
            ..||..:||:| :.|.   ::...:|.|..|.              |.:.||.|..|.:
Worm   378 ENYGFAEVQLL-EKHE---MLNGHLLTRKIELTSGTWKHSDDDPPIRTITHFQFLKWKEGEGLEG 438

  Fly  1437 ------FGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQINTSD--- 1492
                  |...|           .|.|...:  ||:||.|.|.||:..|:..:.:.|.|||..
Worm   439 EMSMDAFNYVN-----------HRTRNNLD--PIIVHSSLGTGRACAFVGAEYMFQMINTKKCGT 490

  Fly  1493 ----YVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVL 1528
                .||       .|.:|:..:|..:|...:......:|
Worm   491 ARFFQVD-------FRTKRLGALQNGKQLFWVQNMAFELL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	74/295 (25%)
		PTPc	1298..1525	CDD:238006	67/269 (25%)
Y54F10BM.3	NP_001368044.1	Y_phosphatase	278..515	CDD:395053	69/276 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910