DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and Y48G9A.9

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_001022893.1	Gene:	Y48G9A.9 / 175343	WormBaseID:	WBGene00021702	Length:	361	Species:	Caenorhabditis elegans

Alignment Length:	339	Identity:	105/339 - (30%)
Similarity:	158/339 - (46%)	Gaps:	57/339 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1219 YKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVG 1283
            |....:...|.|.|.......:|.:.:|...: :.|:..|:.||.:.|..|  .|..||..|.
Worm    35 YDENEHKIYKKTDDHHRKYVETLNNFIIATEK-LGIEGLAKQYRKLDAQQD--SSLTFEAFKQ-- 94

  Fly  1284 RDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPL 1348
                        |..|||:::::..|.:|.|| .:|.....|||:||||..:.....||.|||||
Worm    95 ------------NMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPL 146

  Fly  1349 HSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWVMT 1413
            ..|..|||||.::..:.:|:||.:..|:||.||..|||:..|...||.|:|..:.:|      ..
Worm   147 QHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGES------SD 205

  Fly  1414 EFMLCRGS------------------EQRILRHFHFTTWPDFGVPNP-----PQTLVRFVRAFRD 1455
            ||.:|..:                  |.|: ....:..|||.|||:.     ||.|:..||
Worm   206 EFEICNLAVTFVPDNVPVDEQPANLKELRV-NLIKWPNWPDRGVPDEKCHTVPQRLLAQVR---- 265

  Fly  1456 RIGAEQRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICI 1520
                 ..|.|||||||:||:|..:.|:....:::....||...|:..:||:|...:|||.||:.|
Worm   266 -----HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYI 325

  Fly  1521 HQCLLAVLEGKENI 1534
            |:.::|...|:.::
Worm   326 HRVMIAFARGETDV 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	91/275 (33%)
		PTPc	1298..1525	CDD:238006	86/249 (35%)
Y48G9A.9	NP_001022893.1	PTPc	71..330	CDD:214550	96/291 (33%)
Y48G9A.9	NP_001022893.1	PTPc	97..330	CDD:238006	86/249 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910