DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptp10D and M05D6.3

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_495789.1	Gene:	M05D6.3 / 174355	WormBaseID:	WBGene00010876	Length:	397	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	67/308 - (21%)
Similarity:	122/308 - (39%)	Gaps:	65/308 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1287 PCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHS- 1350
            |.|:.....|...||..::..:||||.:|.|.|..:  |:.||::|.|::....:|..|.|.:.
Worm    81 PNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNDH 143

  Fly  1351 TRDDFWRMCWESNSRAIVMLTRCFEKGREK--------------------------------CDQ 1383
            |...||||..|.....|::.....||.:.|                                |.:
Worm   144 TEYIFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRGFEKSFLHEFGAKSLEECELKAKICRK 208

  Fly  1384 YWPNDTVPVFYGDIKVQILNDSHYADWVMTEFMLC----RGSEQRILRHFHFTTW------PDFG 1438
            :||.......:..:.:|..:|  :::..|..|.|.    :...|.:|.||:  .|      |::.
Worm   209 FWPEKRSKKDFPTLSIQASDD--HSETHMKTFNLTVTEKKQDHQTVLMHFY--EWADASKLPEYM 269

  Fly  1439 VPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAM 1503
            :.......::::|:.: :.|....||::.|:.||.:.....|:|.|:.:|.....|.....:.|:
Worm   270 LDMRASIKLQYIRSSK-KTGVCIGPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAI 333

  Fly  1504 RKERVWMVQTEQQYICIHQCLL--AVLEG-------------KENIVG 1536
            :.:|....:|...|....:.|:  ||..|             :::|||
Worm   334 KMQRFGCFRTVGPYSTACEMLMKFAVTTGVVHDAAIGEKPKPQKSIVG 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	60/280 (21%)
		PTPc	1298..1525	CDD:238006	57/269 (21%)
M05D6.3	NP_495789.1	PTPc	83..356	CDD:214550	60/279 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910