DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and C33F10.8

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_494864.2	Gene:	C33F10.8 / 173829	WormBaseID:	WBGene00016356	Length:	463	Species:	Caenorhabditis elegans

Alignment Length:	325	Identity:	72/325 - (22%)
Similarity:	125/325 - (38%)	Gaps:	78/325 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1223 RNNCRKTTKDSRAND-----NMSLPDSV-IEQNRPILIKNFAEHYRLMSADSDFRFSEEF--EEL 1279
            :.|.:.||.::...|     .:...|.| ..:|...|...|:.|  ||:.....| |:.|  ...
Worm   115 KTNWKTTTTETEDEDVAGQKYIKFMDQVAFIENGTTLSTFFSNH--LMNIAPTSR-SDAFHGNTF 176

  Fly  1280 KHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVT 1344
            |:..:|.||                   .|.:|.||.   |.....||:||::...:..:.:|.|
Worm   177 KNQRKDVPC-------------------IDDTRVKLA---DPNIVYYIHANHIMFDHLKKTYITT 219

  Fly  1345 QGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHYAD 1409
            |.||..|.:|||.|..:.....||.||.......       || ..|::|.: |.:..|  ::..
Worm   220 QHPLPGTLNDFWAMVADQKVETIVSLTSSSSASN-------PN-VYPMYYPN-KPETFN--NFGQ 273

  Fly  1410 WVMTEFMLCR-----------------------GSEQRILRHFHFTTWPDFGVPNPPQTLVRFVR 1451
            :    |:.|:                       ..|:|.:|.:|:..|....||...:.::..|:
Worm   274 F----FVYCKTVTQPKTKYGCKEYKFELVVQADNEERRSVRLYHYPHWTKNMVPASSKVVLNLVK 334

  Fly  1452 AFRDRIGAE--QRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTE 1514
                :||.:  |.|:||.|..||.:|...:.:|.:...:.....|: |.:::...:.:..:..|:
Worm   335 ----KIGKKKSQAPVVVQCETGVNQSAELVFVDAMCTLLTRQVEVN-FDVLFRQMRSQKALAMTQ 394

Fly 1515 1514
Worm 395 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	59/270 (22%)
		PTPc	1298..1525	CDD:238006	53/242 (22%)
C33F10.8	NP_494864.2	PTPc	164..406	CDD:214550	60/274 (22%)
C33F10.8	NP_494864.2	PTPc	177..400	CDD:238006	57/260 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910