DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and F25H5.7

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	NP_492454.1	Gene:	F25H5.7 / 172740	WormBaseID:	WBGene00009129	Length:	490	Species:	Caenorhabditis elegans

Alignment Length:	328	Identity:	84/328 - (25%)
Similarity:	149/328 - (45%)	Gaps:	23/328 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly  1220 KRRRNNCRKTTKDSRANDNMSLPDSVIEQNR--PILIKNFAEHYRLMSADSDFRFSEEFEELKHV 1282
            :.::...:|..|:.:.|.:    :||.|.|.  |....:..:.:...:|....:...:..:.|..
Worm   128 EEKKEQSKKVNKEKKMNKS----ESVDEDNEQPPEPGSDPRKIWAFKAAKMKCQAISKLHQDKIK 188

  Fly  1283 GRDQP-CTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANY--VPGHNSPREFIVT 1344
            |...| ||:.....|...||:.::...:.:|..|:..|    .|||:|::  :||.:. ..:|.|
Worm   189 GYMPPNCTYTAYDANPDLNRYADVRCIEETRVVLKNHD----RDYIHASWMRMPGKDQ-STYITT 248

  Fly  1345 QGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVF-YGDIKVQI--LNDSH 1406
            ||||..|..|||.|.::.....::||...||.|.|||..|:|.....|. :|..::.:  ..:..
Worm   249 QGPLPETLSDFWHMIYQEKIAYVLMLCTLFEGGVEKCALYYPEKLGEVVKFGKYEITLTECKEEA 313

  Fly  1407 YADWVMTEFMLCR----GSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVH 1467
            .|..:.....:..    .||...:.|.....|||...|...:.::...:..: ::..::.||.||
Worm   314 IAGTIWNALTVTNTEDASSEPLYMNHVQVPWWPDQLAPEDARPMIELYKWVK-KVNPKETPICVH 377

  Fly  1468 CSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKE 1532
            |||||||:.||:.:|....:|..:..:::..||..||..|...||:..|::.::..|:....| |
Worm   378 CSAGVGRTATFVGIDYATIRIMENPNIEMLDIVREMRAMRFQAVQSHMQFLFLYVVLMEYFIG-E 441

  Fly  1533 NIV 1535
            .:|
Worm   442 GVV 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	71/262 (27%)
		PTPc	1298..1525	CDD:238006	65/235 (28%)
F25H5.7	NP_492454.1	PTPc	192..436	CDD:214550	70/249 (28%)
F25H5.7	NP_492454.1	PTPc	205..436	CDD:238006	66/236 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910