DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp10D and XB5906919

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	XP_002939016.3	Gene:	XB5906919 / 100497391	XenbaseID:	XB-GENE-5906920	Length:	578	Species:	Xenopus tropicalis

Alignment Length:	495	Identity:	97/495 - (19%)
Similarity:	159/495 - (32%)	Gaps:	184/495 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   658 GVES-PVPQEVNTTVPPNPVSNIIQLVDSRNITLEWPK--------PEGRVESYILKWWPSDNPG 713
            |.:| ||   :|..:|  ||...:...::||..|...:        .:|..||.||
Frog    43 GAQSYPV---INGDIP--PVCRHVYEANARNSQLCGHRYAELINKIKQGGGESAIL--------- 93

  Fly   714 RVQTKNVSENKSADDLSTVRVLIG-----ELMP----GVQYKFDIQTTSYGILSGITSLYPRTMP 769
                ::...||.......:|:|:.     ||.|    |:.|.   ...|.|.|:|:..:......
Frog    94 ----RHTQRNKKLLVRERLRMLLDDESFLELSPMAGLGLPYG---DVPSAGCLTGVGKICGVWCV 151

  Fly   770 LIQSDVVVANGEKEDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGL 834
            .|.:|..|..|             |..|.|..|           ::|.:|         :.....
Frog   152 FISNDATVKGG-------------TAYPISVKK-----------QLRAQE---------IAIQNR 183

  Fly   835 VPGRLYNITVWTVSGGVASLPIQRQDRLYPEPITQLHATNITDTEISLRWDLPK----------- 888
            :|      ||:.|..|.|.||:|.:  |:|:  .|.......:..|.....:|:
Frog   184 LP------TVYLVDSGGAFLPLQAE--LFPD--KQHGGRTFYNEAIMSAMKIPQVAVVCGSCTAG 238

  Fly   889 GEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVVVRSGTESSVLRSSSPLSASFTT 953
            |.|                 :.|..|.|:            :|.:.||   :..:..||..:.|.
Frog   239 GAY-----------------IPTMAEETV------------IVDKIGT---IFLAGPPLVKAATG 271

  Fly   954 NEA-------------VPGRVERFHPTDVQP--------SEINF--------EWSLPSSEANGVI 989
            .:.             |.|.|:.|..|:.:.        |.:||        |:..|..:||.:.
Frog   272 EDVSAENLGGAKLHSRVSGCVDHFASTEAEAYTCARHIISSLNFDPVPEDSSEYENPLYDANELT 336

  Fly   990 RQFSIAYTNINNL-----------------TDAG---MQDFESEEA--FGVIKNLKPGE-TYVFK 1031
            ....:.|.:..|:                 .|.|   :..|.|.|.  .|::.|  .|| |:...
Frog   337 GLAPLNYKSTLNIKLILSRLLDGSRLLEFKADYGTTLVAGFASVEGNLVGIVAN--NGELTHDAS 399

  Fly  1032 IQAKTAIGFGPEREYRQTMPILAPPRPATQ-VVPTEVYRS 1070
            ::....:....:|    .:|:|.....|:| .|||.|.::
Frog   400 LKGSHFVQLCNQR----GIPLLFLQNTASQESVPTNVVKA 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020	5/13 (38%)
		fn3	683..753	CDD:278470	17/86 (20%)
		fn3	787..850	CDD:278470	10/62 (16%)
		fn3	866..935	CDD:278470	9/79 (11%)
		fn3	961..1043	CDD:278470	22/120 (18%)
		PTPc	1272..1525	CDD:214550
		PTPc	1298..1525	CDD:238006
XB5906919	XP_002939016.3	PLN02820	63..578	CDD:178415	89/470 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001181
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000