Protein Alignment Ptp10D and ptprbl

DIOPT Version :9

• Sequence 1: NP_996413.2
• Gene: Ptp10D / 32115
• FlyBaseID: FBgn0004370
• Length: 1990
• Species: Drosophila melanogaster
• Sequence 2: XP_021326526.1
• Gene: ptprbl / 100333658
• ZFINID: ZDB-GENE-130522-4
• Length: 931
• Species: Danio rerio
• Alignment Length: 1088
• Identity: 275/1088 - (25%)
• Similarity: 426/1088 - (39%)
• Gaps: 264/1088 - (24%)

  Fly   233 LLVLWQPPYPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGLVPGRAYNISVQTMSE 297
            |.|.|:.  ..|....|.||:...:.....|.|.|..     .:..||.||.||.||||: |...
Zfish    26 LSVSWRA--AEGDVDSYWVSLRDRERTVHTLTVSKVS-----TECVFKSLVSGRLYNISI-TSRS 82

  Fly   298 DEISLPTTAQYRTVPLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATT---RRQSTV 359
            .|....|..|.||.|...||.|... .......:|.|...:|  :||.|.||:...   .:..||
Zfish    83 GEFENHTAVQERTQPSPVLNPTATH-MAEEQLLKVYWRHAEG--DFDYYHVSIKHNNIFHQNRTV 144

  Fly   360 PRSNEPVAFFDFRDIAEPGKTFNVIVKTVSGKVTSWPATGDVTLRPLPVRNLRSINDDKTNTMII 424
            |:|.....|...    .||:.:.|.|.|.|||..|..:|...|| |..|:|| |:.|..|..:::
Zfish   145 PKSQNEYVFSGL----VPGRLYMVTVSTWSGKYESSVSTHGSTL-PARVQNL-SLADSGTEDLLV 203

  Fly   425 TWEADPASTQD-EYRIVYHELETFNGDTSTLTTDRTRFTLESLLPGRNYSLSVQAVS-------- 480
            ||.:.|..... |.::::::::.|  ...|||:..|::.|.||.|||.|.:.|...|
Zfish   204 TWASAPGDVDHYEVQLLFNDMKVF--PPITLTSSTTQYLLSSLTPGRLYKILVSTFSGPNLRVQF 266

  Fly   481 ---KKMESNETSIFVVTRPSSPIIEDLKSIRMGLNISW---KSDVNSKQEQYEVLYSRNGTSDLR 539
               :.:.|...:|.:.....|          ..|.:||   :.||    ::|.|..|..
Zfish   267 LRGRTVPSTVKNIHISNEGQS----------SSLRVSWTPGQGDV----DRYTVSLSPG------ 311

  Fly   540 TQKTKESRLVIK--------NLQPGAGYELKVFAVSHDLRSEPHAYFQAVYPNPPRNMTIETVRS 596
                 :.|.|.|        :||||..|.:.|.::|..|.:...|..:.| |:|...:.:|..||
Zfish   312 -----QERFVPKHVNEVSFQHLQPGQQYNITVTSISGSLINNSTATGRTV-PSPVSALQLEEQRS 370

  Fly   597 NSVL-VHWSPPESGEFTEYSIRYRTDSEQQWVRLPSVRSTEAD-----ITDMTKGEKYTIQVNTV 655
            .|.| |.|   ::|:....|.|.:...|:.  .|.|..||.|.     .|.:|.|:.|.:.:..:
Zfish   371 TSTLSVFW---QAGQGVFDSFRLQLLDERG--TLVSNISTAAQAIQHTFTHLTPGKPYRVLIRAL 430

  Fly   656 SFGVESPVPQEVNTTVPPNPVSNIIQLVD-SRNITLEWPKPEGRVESYILKWWPSDNPGRVQTKN 719
            |.||.|. ..||.....|..||::..:.: :.:::..|..|.|..:.:.:..:..|       :.
Zfish   431 SGGVSSN-DVEVEGRTCPATVSDLSVISNTTTSLSFRWAPPVGEFDGFDVLLYDED-------ER 487

  Fly   720 VSENKSA--DDLSTVRVLIGELMPGVQYKFDIQTTSYGILSGITSLYPRTMPLIQSDVVVANGEK 782
            :.:.||.  .|.|.:     .|.||:.||..|.|.| |..:..||::.||:|   :.|...:.:.
Zfish   488 LLDQKSGVMQDCSFL-----NLRPGLLYKVLIFTRS-GDQTNSTSIWARTVP---AAVTFLHADS 543

  Fly   783 EDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGLVPGRLYNITVWTV 847
            ....:::.||:.....:.|.:.:  ..|.....|..|:......|...|..||.||||...|.|.
Zfish   544 RRSSESLWLSWKQPAGAVSSYTL--LILNPDGTRTAEQSLGPDSRSHQFQSLVSGRLYQAVVLTH 606

  Fly   848 SGGVASLPIQRQDRLYPEPITQLHATNITDTEISLRWDLPKG-EYNDFDIAYLTADNLLAQNMTT 911
            ||.:.:: ....||..|:|........||:|.:.:.|..|:. :|:|||:.:...|:|
Zfish   607 SGDLTNM-ATTSDRTDPKPPVSFSFGEITNTSLEITWSAPENTDYDDFDLQWSPRDHL------- 663

  Fly   912 RNEITISDLRPHRNYTFTVVVRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINF 976
                  |...|:.                    ||.||:
Zfish   664 ------SVFNPYH--------------------SPTSAN-------------------------- 676

  Fly   977 EWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFG 1041
                                                    .::|.:.||..|  .|..:|..|.|
Zfish   677 ----------------------------------------RILKGMHPGRQY--NISLRTVSGAG 699

  Fly  1042 PEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAE-DDAKNA 1105
            ....  :.:.|..||.|..::....|..:.|||..:|..::|||.||.|:.:||::.| ||::..
Zfish   700 TNNP--RVLVISGPPLPMARIDENAVTITKSTILFQFNCSWFSDINGAVKFFTIVIIESDDSERQ 762

  Fly  1106 SGLE---MPSWLDVQSYSVWLPYQA------IDPYYPFENRS-VEDFTI----GTEN----CD-- 1150
            ...:   :||:||.:|.|....||.      .|     |::| .::|.:    |.|:    ||
Zfish   763 QPQQVHPLPSYLDYRSNSSIKAYQTSFFRSHCD-----ESQSPAQEFRVQLGSGMESLGGRCDQK 822

  Fly  1151 ------NHKIGYCNGPLKSGTTYRVKVRAFT---GADK-------FTDTAYSFPIQTDQDNTS-L 1198
                  ..:..:|:||||..|.||:.|||||   ..|:       :|||..|.|:.|..:..| :
Zfish   823 TSTGGSQEQTAFCDGPLKPRTAYRLSVRAFTKLYDEDREEFLSPLYTDTYLSKPLLTHAEPLSGV 887

  Fly  1199 IVAITVPLTII--LVLLVTLLFYKRRRNNCRKTTKDSRAND---NMSL 1241
            |..::..|.:|  :|.|:.||.       ||:......|.:   .|||
Zfish   888 IEGVSAGLFLIATMVGLIVLLV-------CRQKVHKMSAQEPVVRMSL 928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470	22/70 (31%)
		fn3	315..391	CDD:278470	22/78 (28%)
		FN3	405..494	CDD:238020	27/100 (27%)
		FN3	511..574	CDD:238020	19/73 (26%)
		FN3	583..671	CDD:238020	28/93 (30%)
		fn3	683..753	CDD:278470	15/72 (21%)
		fn3	787..850	CDD:278470	17/62 (27%)
		fn3	866..935	CDD:278470	14/69 (20%)
		fn3	961..1043	CDD:278470	8/81 (10%)
		PTPc	1272..1525	CDD:214550
		PTPc	1298..1525	CDD:238006
ptprbl	XP_021326526.1	fn3	11..86	CDD:306538	22/67 (33%)
		fn3	98..175	CDD:306538	24/83 (29%)
		fn3	188..259	CDD:306538	23/73 (32%)
		fn3	274..343	CDD:306538	20/93 (22%)
		fn3	358..433	CDD:306538	22/79 (28%)
		FN3	450..520	CDD:328772	18/82 (22%)
		fn3	624..699	CDD:306538	25/175 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16347at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010