Protein Alignment Met and ncoa1

DIOPT Version :10

• Sequence 1: NP_511126.2
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_691744.6
• Gene: ncoa1 / 563288
• ZFINID: ZDB-GENE-041001-175
• Length: 1350
• Species: Danio rerio
• Alignment Length: 767
• Identity: 149/767 - (19%)
• Similarity: 236/767 - (30%)
• Gaps: 257/767 - (33%)

  Fly    26 SGSGSSSDPANGREARN-----------LAEKQRRDKLNASIQELATM----VPHAAESSRRLDK 75
            |.:|.::...|..|:|.           ..||:||:.....|.|||.:    :...|..:.:.||
Zfish     5 SAAGENALDPNILESRKRKGSPCDTSGPSVEKRRRELECRYIDELAELLSANMSDIASLNVKPDK 69

  Fly    76 TAVLRFATHGLRLQYVFGKSASRRRKKTG--------LKGTGMSASPVGDLPNPSLHLTDTLMQL 132
            ..:|:....  ::|.:     .||.::..        ::.:.:|:|..|.:...:  |...|::.
Zfish    70 CHILKSTVD--QIQQI-----KRREQENAALMSPNDEVQQSDISSSSHGMVEKEA--LGPLLLEA 125

  Fly   133 LDCCFLTLTCSGQIVLVSTSVEQLLGHCQSDLYGQNLLQITHPDDQDLLRQQLIPRDIETLFYQH 197
            ||..|..:...|:||.||.:|...||:.|.:|...::..|.|..|.:...:.|:|:   :|....
Zfish   126 LDGFFFVVNREGRIVFVSENVTGYLGYTQEELMTSSVYSILHVGDHNEFVRILLPK---SLVNGV 187

  Fly   198 QHHQQQGHNPQQHSTSTSASTSGSDLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAH 262
            ...|:||   :::|.:.:........:|.:.|.:|   .|||.|.
Zfish   188 PWSQEQG---RRNSHTFNCRLLKRPPDEVDSENQE---ARQQYEL-------------------- 226

  Fly   263 LATIDDRLRMDRRCFTVRLARASTRAEATRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQL--- 324
                       .:||||...:|...       |...:..|..        ..|...|...|:
Zfish   227 -----------MQCFTVSQPKALQE-------EGEDLQSCLI--------CIACRIPRPPQIPVS 265

  Fly   325 ----IRRSRNNNMLAAAAAVAAEAATVPPQHDAIAQA--ALHGISGNDIVLVAMARVLREERPPE 383
                |.:......:.:....|..|...|...|.:.:.  |.....||:   .:.|:.|..|   .
Zfish   266 TESFITKQDPTGKIISIETSALRATGRPGWEDLVRKCIYAFFQPQGNE---PSHAKKLLHE---V 324

  Fly   384 ETEGTVGLTIYRQPEPYQLEYHTRHLIDGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRW 448
            .|.|.....:||..           |.||:.:....|               ..||.....||:.
Zfish   325 MTHGMAISPLYRFT-----------LSDGTSLSAQTR---------------CKFCCPQNPDVQP 363

  Fly   449 VIVALRQMYDCNSDYGESCYRLLSRNGRFIYLHTKGFLEVDRGSNKVHSFLCVNTLLDEEAGRQK 513
            .|:                                ||..:||..|
Zfish   364 FIM--------------------------------GFHTIDREHN-------------------- 376

  Fly   514 VQEMKEKFSTIIKAEMPTQS-SSPDLPASQAPQQLERIVLYLIENLQKSVD-------SAETVGG 570
                     |....|..|.| |||..|.|::|.            ||.|.|       :..|...
Zfish   377 ---------TASSQENTTPSLSSPAAPPSRSPA------------LQPSSDLSIHLNNTNGTCAT 420

  Fly   571 QGMESLMDDGYSSPANTLTLEEL-APSP-------TPALALVPPAPSSVKSSISKSVSVVNVTAA 627
            .|..:....||.:|:.....::: :|||       ||. :.:.|.|......::.|..|.....:
Zfish   421 PGPLTPTPPGYLTPSRVGPSQQVSSPSPLGSPLTATPT-SFMSPRPPRGSPGLASSPRVPGHPFS 484

  Fly   628 RKFQQEHQKQRERDREQLKERTNSTQGVIRQLSSCLSEAETASCILSPA---------------- 676
            ......|.......|:|     :...||...|.|.|...:|.:...|||
Zfish   485 PSTPSIHSPAGGLTRQQ-----SGGDGVGFSLPSPLPPRQTPTPSSSPARQPPAKPPEASNDEPK 544

  Fly   677 -------------SSLSASEAPDTPDPHSNTSPPPSLHT----RPSVLHRTL 711
                         ...||.|....|.| |.||..|:.|:    |..:|||.|
Zfish   545 SNQVGNPKLSQLLDGASAPEQDSQPRP-SPTSQCPASHSSLTERHKILHRLL 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_511126.2	bHLH_PAS	38..89	CDD:381397	14/65 (22%)
		PAS	137..>186	CDD:238075	14/48 (29%)
		PAS_11	401..510	CDD:464214	14/108 (13%)
ncoa1	XP_691744.6	None