Protein Alignment Met and arnt

DIOPT Version :10

• Sequence 1: NP_511126.2
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001428910.1
• Gene: arnt / 493634
• ZFINID: ZDB-GENE-060126-7
• Length: 747
• Species: Danio rerio
• Alignment Length: 738
• Identity: 146/738 - (19%)
• Similarity: 263/738 - (35%)
• Gaps: 185/738 - (25%)

  Fly     2 AAPETGNTGSTGSAGSTGSGSG-------------------------SGSGSGSSSDPANGREAR 41
            |.|:.....|.....|.||.|.                         ...|.||:......||..
Zfish     4 ANPDMSEVPSLAMTSSNGSHSNGVQKANKRQATSDYEDDEGGKLFRCDDDGGGSNDKERFARENH 68

  Fly    42 NLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQYVFGKSASRRRKKTGLK 106
            :..|::||:|:.|.|.||:.|||..:..:|:.||..:||.|...::                .|:
Zfish    69 SEIERRRRNKMTAYITELSDMVPACSALARKPDKLTILRMAVSHMK----------------SLR 117

  Fly   107 GTGMSASPVGDLPNPSLHLTD-----TLMQLLDCCFLTLTC-SGQIVLVSTSVEQLLGHCQSDLY 165
            |||.:::.....|:   .|||     .:::..|.....::| :|::|.||.||..:|...|||..
Zfish   118 GTGNTSTDGTYKPS---FLTDQELKHLILEAADGFLFVVSCETGRVVYVSDSVTPVLNQAQSDWL 179

  Fly   166 GQNLLQITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTSTSASTSGSDLEEEEMET 230
            |.:|....||||.:.||:||                         ||:.:.:.||..|   :|:|
Zfish   180 GSSLYDQLHPDDVEKLREQL-------------------------STTENNNNSGRML---DMKT 216

  Fly   231 EEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDRRCFTVRLARASTRAEATRHYE 295
              ..:.::.|:|                                   |||::..:.|:...|
Zfish   217 --GTVKKEGGQA-----------------------------------TVRMSMGARRSFICR--- 241

  Fly   296 RVKIDGCFRRSDSSLTGGAAANYPIVSQLIR--RSRNNNMLAAAAAVAAEAATV---------PP 349
                          :..|.....|:....:.  |:||.|.|.:|.....:...|         ||
Zfish   242 --------------MRCGVCPVEPVSLNRLNFLRTRNRNGLGSAKDGEQQYVVVHCTGYIRSWPP 292

  Fly   350 QHDAIAQAALHGISGNDIVLVAMARVLREERPPEETEGTVGLTIYRQPEPYQLEYHTRHLIDGSI 414
            ....:::.......||...|||:.|:.....|.:.:...:.:.:         |:.:||...|..
Zfish   293 AGMNLSEEEADNNQGNRFCLVAIGRLQVTCCPSDTSINNISVPV---------EFISRHNSQGVY 348

  Fly   415 IDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYDCNSDYGESCYRLLSRNGRFIY 479
            ...|.|.....|:...|:...:...|.|.:|...:..:|:|:...........:|..|::..:::
Zfish   349 TFVDHRCTATVGFQTQELLGKNILDFAHPEDQGLLRDSLQQVVKLRGQVMSVMFRFQSKSREWVW 413

  Fly   480 LHTKGFLEVDRGSNKVHSFLCVNTLLDEEAGRQKVQEMKEKFSTIIKAEMPTQSSSPDLPASQAP 544
            :.|..|...:..|.::...:|.||.::..:....|..:..          |:...||:.|::.:|
Zfish   414 MRTSSFTFQNPFSEEIEYIICTNTNVNRGSSEGSVSPLSS----------PSLGQSPNCPSTPSP 468

  Fly   545 QQLERIVLYLIENLQKSVDSAETVGGQGMESLMDDGYSSPANTLTLEELAPSPTPALALVPPAPS 609
               ..:.:..::..|..:|.    ||...|:..::      :.:.|.:::.. |..:.....:..
Zfish   469 ---GCVTVRQLQQQQVELDG----GGMSQETPYEN------SQVALPQVSVQ-TCGVVSADHSSK 519

  Fly   610 SVKSSISKSVSVVNVTAARKFQQEHQKQRERDREQLKERTNSTQGVIRQLSSCLSEAETASCILS 674
            :|.||:|....|....||  |....:.........|.::.........|:.:.:|...|.|.:
Zfish   520 AVSSSVSSGQQVYPPAAA--FPSPARPTETFRSPVLPQQMVPVAHSAGQMLAQMSRQSTPSGV-- 580

  Fly   675 PASSLSASEAPDTPDPHSNTSPP 697
            ..|:.|..:||..|     |:||
Zfish   581 SGSNNSPIQAPSGP-----TAPP 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_511126.2	bHLH_PAS	38..89	CDD:381397	19/50 (38%)
		PAS	137..>186	CDD:238075	20/49 (41%)
		PAS_11	401..510	CDD:464214	21/108 (19%)
arnt	NP_001428910.1	None