Protein Alignment Met and ss

DIOPT Version :10

• Sequence 1: NP_511126.2
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001163629.2
• Gene: ss / 41988
• FlyBaseID: FBgn0003513
• Length: 1015
• Species: Drosophila melanogaster
• Alignment Length: 691
• Identity: 136/691 - (19%)
• Similarity: 235/691 - (34%)
• Gaps: 226/691 - (32%)

  Fly    26 SGSGSSSDPANGREARNLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQY 90
            :|......|.:|....| ..|:.|::|||.:..||:::|.......:||:.::||.:...||.:.
  Fly    16 NGKSLKPPPKDGVTKSN-PSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKS 79

  Fly    91 VFGKSASRRRKKTGL-----KGTGMSASPVGDLPNPSLHLTDTLMQLLDCCFLTLTCSGQIVLVS 150
            .|.....:.::..|:     ...|.....:|...:..|. .|..:|.|:...:.|||.|::...:
  Fly    80 YFQVVMHKDKEDNGVLPHIHAHDGYRTRELGAFEHGLLD-GDMFLQALNGFLMILTCEGEVFFAT 143

  Fly   151 TSVEQLLGHCQSDLYGQNLLQITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTSTS 215
            .|:|..||..|||:..|::.::.|.:|::.|::||:                       .::...
  Fly   144 HSIESYLGFHQSDIVHQSVYELVHSEDREELQRQLL-----------------------WNSFLP 185

  Fly   216 ASTSGSDLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDRRCFTVR 280
            |..|...|.|                            |.:|.:..:|          .|.||||
  Fly   186 ADMSSMQLAE----------------------------TLAPDKALYL----------ERSFTVR 212

  Fly   281 LARASTRAEATRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQLIRRSRNNNMLAAAAAVAAEAA 345
            .   ....:.|..:.|:.|.|..:
  Fly   213 F---RCLLDNTSGFLRLDIRGRIK----------------------------------------- 233

  Fly   346 TVPPQHDAIAQAALHGISGNDIVLVAMARVLREERPPEETEGTVGLTIYRQP--EPYQLE----- 403
                        .|||            :..:.|.||      :.|..|..|  .|..||
  Fly   234 ------------VLHG------------QNRKTEEPP------LALFAYCTPFGPPSLLEIPHKE 268

  Fly   404 --YHTRHLIDGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYDCNSDYGES 466
              :.::|.:|.|::..|||...:.||...|:.|:..:..:|.||:.:|..|.:::....:. |..
  Fly   269 NMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMGGYDLVHYDDLAYVASAHQELLKTGAS-GMI 332

  Fly   467 CYRLLSRNGRFIYLHTKGFLEVDRGSNKVHSFLCVNTLLDEEAGRQKVQEMKEKFSTIIKAEMPT 531
            .||...::|.:.:|.|...|...  ::|....:|.:..|.:|.|...:.:....|.
  Fly   333 AYRYQKKDGEWQWLQTSSRLVYK--NSKPDFVICTHRQLMDEEGHDLLGKRTMDFK--------- 386

  Fly   532 QSSSPDLPASQAPQQLERIVLYLIENLQKSVDSAETVGGQGMESLMDDGYSSPANTLTLEELAPS 596
                               |.||...|..:                   |.|.|:.|.   :.||
  Fly   387 -------------------VSYLDTGLAST-------------------YFSEADQLV---VPPS 410

  Fly   597 PTP-ALALVPPAPSS-----VKSSISKSVSVVNVTAARKFQQEHQKQRERDREQLKERTNSTQGV 655
            .:| |.||.||...:     .|:.:...:|...  :.||.||::|.|           |..|..:
  Fly   411 TSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCR--SKRKLQQQNQPQ-----------TQQTSPL 462

  Fly   656 IRQLSSCLSEAETASCILSPASSLSASEAPDTPDPHSNTSP 696
            ..|:.| .:.|.....:..||::::|  |....:|...|||
  Fly   463 GGQVGS-PAPAVAVEYLPDPAAAVAA--AYSNLNPMYTTSP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_511126.2	bHLH_PAS	38..89	CDD:381397	15/50 (30%)
		PAS	137..>186	CDD:238075	16/48 (33%)
		PAS_11	401..510	CDD:464214	28/115 (24%)
ss	NP_001163629.2	bHLH-PAS_spineless_like	24..87	CDD:381573	18/63 (29%)
		PAS	123..178	CDD:214512	17/54 (31%)
		PAS_3	282..366	CDD:430001	21/86 (24%)