Protein Alignment Met and tgo

DIOPT Version :10

• Sequence 1: NP_511126.2
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_731308.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Alignment Length: 752
• Identity: 161/752 - (21%)
• Similarity: 269/752 - (35%)
• Gaps: 232/752 - (30%)

  Fly    33 DPANGREARNLA--------EKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQ 89
            |.||.::....|        |::||:|:.|.|.||:.|||..:..:|:.||..:||.|...::
  Fly     2 DEANIQDKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMK-- 64

  Fly    90 YVFGKSASRRRKKTGLKGTGMSASPVGDLPNPSLHLTD-----TLMQLLDCCFLTLTC-SGQIVL 148
                          .|:|||.::|.....|:   .|||     .:::..|.....::| ||:::.
  Fly    65 --------------ALRGTGNTSSDGTYKPS---FLTDQELKHLILEAADGFLFVVSCDSGRVIY 112

  Fly   149 VSTSVEQLLGHCQSDLYGQNLLQITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTS 213
            ||.||..:|.:.|||.||.:|.:..||||::.:|:||                           |
  Fly   113 VSDSVTPVLNYTQSDWYGTSLYEHIHPDDREKIREQL---------------------------S 150

  Fly   214 TSASTSGS---DLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDRR 275
            |..|.:..   ||:...::.|.|:                     |..|::..|         ||
  Fly   151 TQESQNAGRILDLKSGTVKKEGHQ---------------------SSMRLSMGA---------RR 185

  Fly   276 CFTVRLARASTRAEATRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQLIRRSRNNNMLAAAAAV 340
            .|..|:...:...|:                             :||..:.|.:..|.|.
  Fly   186 GFICRMRVGNVNPES-----------------------------MVSGHLNRLKQRNSLG----- 216

  Fly   341 AAEAATVPPQHDAIAQAALH--GISGN--------------DI-------VLVAMARVLREERPP 382
                    |..|....|.:|  |...|              |:       .|||:.|:.......
  Fly   217 --------PSRDGTNYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHCCLVAIGRLQVTSTAA 273

  Fly   383 EETEGTVGLTIYRQPEPYQLEYHTRHLIDGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVR 447
            .:..|:..          |.|:.|||.:||.....|||:..:.||...|:.....:.|.|.:|..
  Fly   274 NDMSGSNN----------QSEFITRHAMDGKFTFVDQRVLNILGYTPTELLGKICYDFFHPEDQS 328

  Fly   448 WVIVALRQMYDCNSDYGESCYRLLSRNGRFIYLHTKGFLEVDRGSNKVHSFLCVNTL-------- 504
            .:..:..|:...........||..::|..:::|.|:.:..::..:::|...:|.|:.
  Fly   329 HMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNSSGKTMHGAP 393

  Fly   505 LDEEAGR--QKVQEMKEKFSTI----------IKAEM-PTQSSSPD------LPASQAPQQLERI 550
            ||..|..  ::||:.:::...:          .:.|: |..|::.|      :.|.|||...::
  Fly   394 LDAAAAHTPEQVQQQQQQEQHVYVQAAPGVDYARRELTPVGSATNDGMYQTHMLAMQAPTPQQQ- 457

  Fly   551 VLYLIENLQKSVDSAETVGGQGMESLMDDGYSSPANTLTLEELAPSPTPALALVPPAPSSVKSSI 615
                 :..|:...||:|.         ..||:............|||   ||.:|      ||..
  Fly   458 -----QQQQQRPGSAQTT---------PVGYTYDTTHSPYSAGGPSP---LAKIP------KSGT 499

  Fly   616 SKSVSVVNVTAARKFQQEHQKQR---ERDREQLKERTNSTQG-VIRQLSS---CLSEAETASCIL 673
            |.:....|..||.:.||:.|:|:   |..:.|......|..| ...|||:   ...:|:..:...
  Fly   500 SPTPVAPNSWAALRPQQQQQQQQPVTEGYQYQQTSPARSPSGPTYTQLSAGNGNRQQAQPGAYQA 564

  Fly   674 SPASSLSA------SEAPDTPDPHSNTSPPPSLHTRP 704
            .|....:|      .:|...|.|...|:.|...|..|
  Fly   565 GPPPPPNAPGMWDWQQAGGHPHPPHPTAHPHHPHAHP 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_511126.2	bHLH_PAS	38..89	CDD:381397	18/58 (31%)
		PAS	137..>186	CDD:238075	20/49 (41%)
		PAS_11	401..510	CDD:464214	27/116 (23%)
tgo	NP_731308.1	bHLH-PAS_ARNT	9..74	CDD:381517	22/80 (28%)
		PAS	90..154	CDD:214512	24/90 (27%)
		PAS_11	282..384	CDD:464214	24/101 (24%)