Protein Alignment Met and clockb

DIOPT Version :9

• Sequence 1: NP_001285132.1
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_840080.2
• Gene: clockb / 352927
• ZFINID: ZDB-GENE-030408-2
• Length: 820
• Species: Danio rerio
• Alignment Length: 763
• Identity: 160/763 - (20%)
• Similarity: 275/763 - (36%)
• Gaps: 246/763 - (32%)

  Fly    38 REARNLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQYVFGKSASRRRKK 102
            |.:||.:||:|||:.|..|:||.||:|   .::|::||:.:|:             ||....||.
Zfish    26 RVSRNKSEKKRRDQFNVLIKELGTMLP---GNTRKMDKSTILQ-------------KSIDYLRKN 74

  Fly   103 TGLKGTGMSASPVGDLPNPSL---HLTDTLMQLLDCCFLTLTCSGQIVLVSTSVEQLLGHCQSDL 164
            ........|:....|...|.|   ..:..:::.||..||.:...|.|:.:|.||..||.|..|||
Zfish    75 KENAAQSESSDIKQDWKPPFLSNEEFSQLMLEALDGFFLVMLTDGYIIYISESVTSLLEHLPSDL 139

  Fly   165 YGQNLLQ----ITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTSTSASTSGSDLEE 225
            ..||||.    :.|.:....|..|   .|||.|                          .||..:
Zfish   140 MDQNLLNFLPVVDHGEVYKALSSQ---PDIENL--------------------------NSDYLK 175

  Fly   226 EEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDRRCFTVRLARASTRAEA 290
            .:.:.|                                             |...:.|.|...:.
Zfish   176 SKNQME---------------------------------------------FCCHMLRGSVDPKK 195

  Fly   291 TRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQLIRRSRNNNMLAAAAAVAAEAATVPPQHDAIA 355
            ...||.||..|.|:         :..|.|      :::||.                   .:.|.
Zfish   196 PPVYEYVKFIGNFK---------SLVNMP------QKTRNG-------------------LEGIL 226

  Fly   356 QAALHGISGNDIVLVAMARVLREERPPEETEGTVGLTIYRQPEPYQLEYHTRHLIDGSIIDCDQR 420
            |.:|.....:.:..:|..|:.:.:...|       :.:..:|..   |:.:||.::...:..|.|
Zfish   227 QHSLQPAFDDQLCFIATVRLAKPQFIKE-------MCMVEEPNE---EFTSRHSLEWKFLLLDHR 281

  Fly   421 IGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYDCNSDY-----GESC-YRLLSRNGRFIY 479
            ...:.|||..||...|.:.:.|:||       |..:..|:...     |:|| ||.|::..::|:
Zfish   282 APPIIGYMPFEVLGTSGYDYYHVDD-------LHSLAKCHEHLMQFGKGKSCYYRFLTKGQQWIW 339

  Fly   480 LHTKGFLEVDRGSNKVHSFLCVNTLL---DEEAGRQKVQEMKEKFSTIIKAEMPTQSSSPDLPA- 540
            |.|..::...:.:::....:|.:|::   :..|.|::              ||..:.|.|:|.|
Zfish   340 LQTNYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRR--------------EMGIEESPPELTAD 390

  Fly   541 --SQAPQQLERIVLYLIENLQKS---VDSAETVGGQGMESLMDDGYSSPANTLTLEELAPSPTPA 600
              |.:..||...:..::|....|   ..|:.:.......::.|:..:|..:.|.: :::.||.||
Zfish   391 KISGSETQLNNSLKKVLERFSDSRSPSTSSRSSHKSSHTAISDNTCTSTPSKLHM-DVSSSPRPA 454

  Fly   601 -LALVPPAPSSVKSSISKSVSVVNVTAAR-----KFQQEHQKQRERD------------------ 641
             :.::....|||.   ::|:|..|.|...     ..|.:||:|:.:.
Zfish   455 TVDMISQRRSSVS---TQSMSSQNTTQTDSPVQISQQTQHQQQQPQQPQQVQPNALFSAQLNAMQ 516

  Fly   642 --REQLKERT-------NSTQGVIRQLSSCLSEAETASCIL-SPA-------------------- 676
              :|||::||       ...|..:||:...|...:....|| .||
Zfish   517 HLKEQLEQRTRMIEANIQKQQEELRQIHEQLQRVQGPQMILQQPAQGGGPSVLLPQVGGAQNNIL 581

  Fly   677 -----SSLSASEAPD-TPDPHSNTSPP----PSLHTRPSVLHRTLTST 714
                 :|:.|.:..: |...||.::|.    |...| |..|.:.|.|:
Zfish   582 GIGTQASVVAIQGQNVTSTAHSGSAPQQQTLPQQQT-PRSLQQNLQSS 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_001285132.1	HLH	38..87	CDD:238036	19/48 (40%)
		PAS	137..>186	CDD:238075	20/52 (38%)
		PAS_11	403..510	CDD:291273	27/115 (23%)
clockb	NP_840080.2	HLH	22..76	CDD:238036	23/65 (35%)
		PAS	99..160	CDD:214512	20/60 (33%)
		PAS_11	263..366	CDD:291273	27/112 (24%)
		PAS	264..362	CDD:238075	26/104 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577657
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740