Protein Alignment Met and tai

DIOPT Version :10

• Sequence 1: NP_511126.2
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001245949.1
• Gene: tai / 34242
• FlyBaseID: FBgn0041092
• Length: 2047
• Species: Drosophila melanogaster
• Alignment Length: 852
• Identity: 163/852 - (19%)
• Similarity: 276/852 - (32%)
• Gaps: 287/852 - (33%)

  Fly     2 AAPETGN-TGSTGSAGSTGSGSGSGSGSGSSSDPANGREAR-------NLA---------EKQRR 49
            ||.:|.| ..:...:.:..:...|...:.|::...:||:.|       ||.         ||:||
  Fly   184 AAAQTANLAAALQRSAAIMNAVASPISANSANSATSGRKIRRKTDSKVNLPQSQINKCNNEKRRR 248

  Fly    50 DKLNASIQELA---TMVPHAAESSRRLDKTAVLRFATHGLRLQYVFGKSASRRRKKTGLKGT--- 108
            :..|..|::|:   |:......:|.:.||.|:|.......|  .:..|..:|....|.....
  Fly   249 EAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTYR--EICDKGQNRDISSTSTNNNNST 311

  Fly   109 ----------------------------------------GMSASPVGDLPNPSLHL-----TDT 128
                                                    |..:|....||.|||.|     ...
  Fly   312 TTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPEPSLLLGQVPEISA 376

  Fly   129 LMQLLD-------CCFLTLTCSGQIVLVSTSVEQLLGHCQSDLYGQNLLQITHPDDQDLLRQQLI 186
            ..:.|:       ...|.:..:|.|...:.::..|:|:.:.:||.|.|....:..|...|..
  Fly   377 YFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYSGDHAKLEP--- 438

  Fly   187 PRDIETLFYQHQHHQQQGHN---PQQHSTSTSASTSGSDLEE--------EEMETEEHRLGRQQG 240
              .|.|::...........|   |...|..|||...| ||||        ....:....||...|
  Fly   439 --IINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWG-DLEELNNGNASQGSNSSGAGGLGGAGG 500

  Fly   241 EADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDRRCFTVRLARASTRAEATRHYERVKIDGCFRR 305
            .|...:                 .:|..::||     .|:..|.:|:..:          .|..:
  Fly   501 AAAGKK-----------------RSISTKVRM-----LVKDTRTATQTSS----------NCEEK 533

  Fly   306 SDSSLTGGAAANYPIVSQLIRRSRNNNMLAAAAAVAAEAATVPPQHDAIAQAALHGISGNDIVLV 370
            .                  :|:|.:.:.......:||     |.:.||.|.:::       :.|:
  Fly   534 P------------------LRQSGHQDKYEEVVLIAA-----PVKDDADASSSV-------LCLI 568

  Fly   371 AMARVLREERPPEETEGTVGLTIYRQPEP-----YQLEYHTRHLIDGSIIDCD---------QRI 421
            .        ||.:|:...:.:..:.|.:|     ::|:.|      |.|:..|         |.:
  Fly   569 T--------RPEDESPLEINIQQHVQQQPIEQMTFKLDIH------GKILTLDPTALREPFKQHL 619

  Fly   422 GLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYD---CNSDYGESCYRLLSRNGRF------ 477
            ....|.:..::      |..|  |:..:...||.:.|   .||....:...::||..|.
  Fly   620 QTWVGRLWQDL------CHPH--DLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGAPD 676

  Fly   478 IYLHTKG----FLEVDRGSNKVHSFLCVNTLLDEEAGRQKVQEMKEK-----FSTIIKAEMPTQS 533
            :|:|.|.    ||....|....  .:.|.|||:.|      .:|...     ...:...::...:
  Fly   677 VYVHVKANSRLFLNQTPGEGDF--IMSVQTLLNSE------NDMNSSNTGAGSGGLGLGQLCAMA 733

  Fly   534 SSPDLPASQAPQQLERIVLYLIENLQKSVDSAETVGGQGMESLMDDGYSSPANTLTLEELAPSPT 598
            .||.|.:|            |:.:|  |:|...  ||.|..|     .||||.:..|      ||
  Fly   734 PSPSLASS------------LLSSL--SMDGLH--GGTGSGS-----SSSPAASGML------PT 771

  Fly   599 PAL-ALVPPAP------SSVKSSIS---KSVSVVNVTAARKFQQEHQKQRERDREQLKERTNSTQ 653
            ..| .||....      |:..:|:.   .|.:::|.|..:  ||:.|:||.   ......::|..
  Fly   772 HLLGGLVGGGQQGGGGNSTQTTSVGGPLMSSAIINGTGLQ--QQQQQQQRS---GASSSASSSAN 831

  Fly   654 GVIRQLSSCLSEAE----------------TASCILSPASSLSA--SEAPD------TPDPHSNT 694
            .::...::..:.||                ::|..|.|:..:.|  ...|:      ||   .:|
  Fly   832 ALVNAFTASPAPAEHSFYGSDTFEFDIAAHSSSFELDPSGGVGAWTDSRPNSRASVATP---VST 893

  Fly   695 SPPPSLH 701
            ..|||.|
  Fly   894 PRPPSGH 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_511126.2	bHLH_PAS	38..89	CDD:381397	18/69 (26%)
		PAS	137..>186	CDD:238075	11/48 (23%)
		PAS_11	401..510	CDD:464214	29/130 (22%)
tai	NP_001245949.1	bHLH_SF	239..291	CDD:469605	14/53 (26%)
		PAS	377..442	CDD:214512	13/69 (19%)
		PAS_11	590..711	CDD:464214	29/142 (20%)