Protein Alignment Met and Npas2

DIOPT Version :9

• Sequence 1: NP_001285132.1
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_038939510.1
• Gene: Npas2 / 316351
• RGDID: 1309681
• Length: 855
• Species: Rattus norvegicus
• Alignment Length: 787
• Identity: 165/787 - (20%)
• Similarity: 276/787 - (35%)
• Gaps: 272/787 - (34%)

  Fly    38 REARNLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQYVFGKSASRRRKK 102
            |.:||.:||:|||:.|..|:||::|:|   .::|:||||.||                    .|.
  Rat    11 RASRNKSEKKRRDQFNVLIKELSSMLP---GNTRKLDKTTVL--------------------EKV 52

  Fly   103 TGL--KGTGMSA-SPVGDLP---NPSL----HLTDTLMQLLDCCFLTLTCSGQIVLVSTSVEQLL 157
            .|.  |...:|| :.:.|:.   .||.    ..|..:::.||...:.:|..|.|:.||.|:..||
  Rat    53 IGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLL 117

  Fly   158 GH-------CQSDLYGQNLLQI-----THPDDQ-----------DLLRQQLIPRDIETLFYQHQH 199
            ||       ....|:....|::     .||.::           |::.|.|:.      |...|.
  Rat   118 GHLPGTEEESMKGLHRSRTLRLCLRSEVHPVERASFSLYFLLQSDVMDQNLLN------FLPEQE 176

  Fly   200 HQQ-----QGHNPQQHSTSTSASTSGSDLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRR 259
            |.:     ..|.....|.|.....|.:|||
  Rat   177 HSEVYKILSSHMLVTDSPSPEFLKSDNDLE----------------------------------- 206

  Fly   260 MAHLATIDDRLRMDRRCFTVRLARASTRAEATRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQL 324
                             |...|.|.|...:....||.:|..|.||..:         |.|..|
  Rat   207 -----------------FYCHLLRGSLNPKEFPTYEYIKFVGNFRSYN---------NVPSPS-- 243

  Fly   325 IRRSRNNNMLAAAAAVAAEAATVPPQHDAIAQAALHGISGNDIVLVAMARVLREERPPEETEGTV 389
              .:..:|.|:....|..                     |.::..:|..|:   ..|....|..|
  Rat   244 --CNGFDNTLSRPCRVPL---------------------GKEVCFIATVRL---ATPQFLKEMCV 282

  Fly   390 GLTIYRQPEPYQLEYHTRHLIDGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALR 454
            .      .||.: |:.:||.::...:..|.|...:.||:..||...|.:.:.|:||:.  ::|..
  Rat   283 A------DEPLE-EFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLE--LLARC 338

  Fly   455 QMYDCNSDYGES-CYRLLSRNGRFIYLHTKGFLEVDRGSNKVHSFLCVNTLLDEEAGR-QKVQE- 516
            ..:......|:| |||.|::..::|:|.|..::...:.::|....:|.::::.....| ::.||
  Rat   339 HQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQEL 403

  Fly   517 --------------MKEKFSTI----------IKAEMPTQSSSPDLPA--------------SQA 543
                          :|||.|::          :.|...|.|.||...:              :..
  Rat   404 ALEDPPTEAMHPSALKEKDSSLEPQPHFNALDMGASGLTSSPSPSASSRSSHKSSHTAMSEPTST 468

  Fly   544 PQQLERIVLYLIEN----LQKSVDSAETVGGQGMESLMDDGYSSPANTLT------LEELAPSPT 598
            |.:|      :.||    |.:|....:.:..||    :....:.||..|:      .::|.|...
  Rat   469 PTKL------MAENSTTALPRSATLPQELPVQG----LSQAATMPAPLLSSSSCDLAKQLLPQSL 523

  Fly   599 PALAL-VPPAP---SSVKSSISKSVSVVNVTAARKFQQEHQKQRERDREQLKERTNSTQGVIRQL 659
            |...| .||||   .|.:.|:.:::                      ::||::||...|..||..
  Rat   524 PQTVLQSPPAPVTQFSAQFSMFQTI----------------------KDQLEQRTRILQANIRWQ 566

  Fly   660 SSCLSEAETASCIL----------SPASSLS-------ASEAPDTPDPHSNTSPPPSLHTRPSVL 707
            ...|.:.:...|::          .||.|||       |::.|....|.:.:.||..::|   .|
  Rat   567 QEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSGAQRPAAQQPLQQRPSAPSQPPLVVNT---PL 628

  Fly   708 HRTLTST 714
            ...:|||
  Rat   629 PGQITST 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_001285132.1	HLH	38..87	CDD:238036	21/48 (44%)
		PAS	137..>186	CDD:238075	16/71 (23%)
		PAS_11	403..510	CDD:291273	25/107 (23%)
Npas2	XP_038939510.1	bHLH-PAS_NPAS2_PASD4	1..77	CDD:381580	27/88 (31%)
		PAS	84..234	CDD:395786	38/207 (18%)
		PAS_11	288..391	CDD:405306	25/105 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338227
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740