Protein Alignment Met and Arntl2

DIOPT Version :9

• Sequence 1: NP_001285132.1
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_006507111.1
• Gene: Arntl2 / 272322
• MGIID: 2684845
• Length: 595
• Species: Mus musculus
• Alignment Length: 614
• Identity: 135/614 - (21%)
• Similarity: 227/614 - (36%)
• Gaps: 170/614 - (27%)

  Fly    32 SDPANGREARNLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQYVFGKSA 96
            |.|:..|||.:..||:||||:|..||:|::|:|....::.:|||.:|||.|...||
Mouse    44 SAPSGIREAHSQMEKRRRDKMNHLIQKLSSMIPPHIPTAHKLDKLSVLRRAVQYLR--------- 99

  Fly    97 SRRRKKTGLKGTGMSASPVGDLPNPSL----HLTDTLMQLLDCCFLTLTCS-GQIVLVSTSVEQL 156
            |.|         ||:...:|:...||.    .|:..:::..:.....:.|. |:|..||.||.:.
Mouse   100 SLR---------GMTELYLGENSKPSFIQDKELSHLILKAAEGFLFVVGCERGRIFYVSKSVSKT 155

  Fly   157 LGHCQSDLYGQNLLQITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTSTSASTSGS 221
            |.:.|:.|.||||....||.|...:::||                               |..||
Mouse   156 LRYDQASLIGQNLFDFLHPKDVAKVKEQL-------------------------------SCDGS 189

  Fly   222 DLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDRRCFTVRLARAST 286
            . .|:.::|:..::          ..|||..|   ||  .|..:        ||.|..|:...:.
Mouse   190 P-REKPIDTKTSQV----------YSHPYTGR---PR--MHSGS--------RRSFFFRMKSCTV 230

  Fly   287 RAEATRHYERVKIDGCFRRSD-----SSLTGGAAANYPI-VSQLIRRSRNNNMLAAAAAVAAEAA 345
            ..:     |......|.::.|     :....|...::|: |..:.:.|....
Mouse   231 PVK-----EEQPCSSCSKKKDHRKFHTVHCTGYLRSWPLNVVGMEKESGGGK------------- 277

  Fly   346 TVPPQHDAIAQAALHGISGNDIVLVAMARVLREERPPEETEGTVGLTIYRQPEPYQLEYHTRHLI 410
                            .||....||||.| |.....|::: |.:.:    :|    .|:.||..:
Mouse   278 ----------------DSGPLTCLVAMGR-LHPYIVPQKS-GKINV----RP----AEFITRFAM 316

  Fly   411 DGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYDCNSDYGESCYRLLSRNG 475
            :|..:..|||...:.||:..|:...|.:.:.|.||...:....:.:...........|:...::|
Mouse   317 NGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHSSLTDKHKAVLQSKEKILTDSYKFRVKDG 381

  Fly   476 RFIYLHTKGFLEVDRGSNKVHSFLCVNTLL-----------------DEEAGRQKVQEMK----- 518
            .|:.|.::.|...:..:.::...:.||||:                 ....|:.::|..:
Mouse   382 AFVTLKSEWFSFTNPWTKELEYIVSVNTLVLGRSETRLSLLHCGGSSQSSEGKTELQVRRGNSDA 446

  Fly   519 --EKF--STIIKAEMPTQSSSPDLPASQAPQQLERIVLYLIENLQKSVDSAETVGGQGMESLMDD 579
              :.|  |.|   .:|..|:...|.|......:...||    :||: :.|:........|.:.||
Mouse   447 SSDSFRQSCI---NVPGVSTGTVLGAGSIGTDIANEVL----SLQR-LHSSSPEDASPSEEVRDD 503

  Fly   580 -------GYSSPANTLTLEELAPSPTPAL 601
                   .| .||:|.....::||.|..|
Mouse   504 CSVNGGNAY-GPASTREPFAVSPSETEVL 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_001285132.1	HLH	38..87	CDD:238036	22/48 (46%)
		PAS	137..>186	CDD:238075	18/49 (37%)
		PAS_11	403..510	CDD:291273	23/123 (19%)
Arntl2	XP_006507111.1	bHLH_SF	49..108	CDD:381792	28/76 (37%)
		PAS	125..184	CDD:214512	17/58 (29%)
		PAS_11	309..411	CDD:373151	22/101 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834651
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23042
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840