Protein Alignment Met and arnt

DIOPT Version :10

• Sequence 1: NP_511126.2
• Gene: Met / 32114
• FlyBaseID: FBgn0002723
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_012825275.1
• Gene: arnt / 100144695
• XenbaseID: XB-GENE-855450
• Length: 778
• Species: Xenopus tropicalis
• Alignment Length: 828
• Identity: 170/828 - (20%)
• Similarity: 275/828 - (33%)
• Gaps: 266/828 - (32%)

  Fly     3 APETGNTGSTGSAGSTGS--------GSGSGSGSGSSSDPAN----------------------- 36
            |..|||.||:|.||  ||        .||.........|.:|
 Frog    11 AVSTGNPGSSGQAG--GSMVQRTNKRRSGLDFDDDDDDDSSNKFLRCDDDQLPNDKERFARSDDE 73

  Fly    37 ---------GREARNLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQYVF 92
                     .||..:..|::||:|:.|.|.||:.|||..:..:|:.||..:||.|...::
 Frog    74 QSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMK----- 133

  Fly    93 GKSASRRRKKTGLKGTGMSASPVGDLPNPSLHLTD-----TLMQLLDCCFLTLTC-SGQIVLVST 151
                       .|:|||  .:|......||. |||     .:::..|.....::| :|:||.||.
 Frog   134 -----------SLRGTG--NTPTDGTYKPSF-LTDQELKHLILEAADGFLFVVSCETGRIVYVSD 184

  Fly   152 SVEQLLGHCQSDLYGQNLLQITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTSTSA 216
            ||..:|...||:.:|..|....||||.|.||:||                         ||:.:|
 Frog   185 SVTPVLNQPQSEWFGSTLYDQVHPDDLDKLREQL-------------------------STAENA 224

  Fly   217 STSG-SDLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRM---DRRCF 277
            .|.. .||:...::.|    |:|..                             :||   .||.|
 Frog   225 MTGRILDLKTGTVKKE----GQQSS-----------------------------MRMCMGSRRSF 256

  Fly   278 TVRLARASTRAEATRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQL-IRRSRNNNMLAAAAAVA 341
            ..|:.                   |         |.|......:::| ..|:|..|.|..:....
 Frog   257 ICRMR-------------------C---------GNAVIEPSSMNRLSFMRNRCRNGLGPSKDGE 293

  Fly   342 AEAATV---------PPQHDAIAQAALHGISGNDIVLVAMARVLREERPPEETEGTVGLTIYRQP 397
            .:...|         ||....:.:........:...|||:.|:.....|......||     .||
 Frog   294 PQFVVVHCTGYIKAWPPAGVTLPEDDPDAGQSSKFCLVAIGRLQVTSSPTCTDINTV-----CQP 353

  Fly   398 EPYQLEYHTRHLIDGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYDCNSD 462
                :|:.:||.:||.....|.|.....||...|:.......|.|.:|.:.:..:.:|:......
 Frog   354 ----IEFISRHGVDGLFTFVDHRCTATVGYQPQELLGKDIVEFAHPEDQQLLRDSFQQVVKLKGQ 414

  Fly   463 YGESCYRLLSRNGRFIYLHTKGFLEVDRGSNKVHSFLCVNTLLDEEAGRQKVQEMKEKFSTII-- 525
            .....:|..|:...::.:.|..|...:..|:::...:|.||.:     :...||.:...::.|
 Frog   415 VLSVMFRFRSKTREWLLMRTSSFTFQNPYSDEIEYIICTNTNV-----KNSNQEPRPALASTIQR 474

  Fly   526 --------------KAEMPTQSSSPDLPASQAPQQLERI------------------VLYLIENL 558
                          :.::|.:...|     |||.|.:.:                  |...:.:.
 Frog   475 PPLGPSINHPMDMGQTQLPGRQQQP-----QAPPQTDVVPSREGLGSYNHTQVPVQPVSAAVSDH 534

  Fly   559 QKSVDSAETVGGQGMESLMDDGYSSPANTLTLEELAPS--------------------------- 596
            .|.::..|.:.||..:....:.||: .|:...:.|.||
 Frog   535 SKPLEKTEGMYGQERDPRFAEIYSN-INSDQSKSLNPSGVSGNQQLFQQSSTFTSAPRPVESFRS 598

  Fly   597 ----PTPALALVPPAPSSVKSSISKSVSVVNVTAARKFQQEHQKQRERDREQLKERTNSTQGVIR 657
                |.|::...|.:...:.:.||:..|...||..   ......:.....:|:..:|..||.  .
 Frog   599 GGMVPQPSIIQQPVSAGQILAQISRHTSPTQVTGT---NWSSGTRPSFTAQQVPTQTPKTQA--S 658

  Fly   658 QLSSCLSEAETASCILSPASSLSASEAPDTPDPHSNTSPPPSLHTRPS 705
            |......:|..:|  .||.||.|::.:|       ..:|.||:..|.|
 Frog   659 QFGMGNFQATPSS--FSPLSSQSSTASP-------AGAPYPSMTGRTS 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Met	NP_511126.2	bHLH_PAS	38..89	CDD:381397	19/50 (38%)
		PAS	137..>186	CDD:238075	21/49 (43%)
		PAS_11	401..510	CDD:464214	22/108 (20%)
arnt	XP_012825275.1	bHLH-PAS_ARNT	79..143	CDD:381517	23/81 (28%)
		PAS	156..262	CDD:395786	38/182 (21%)
		PAS_11	355..461	CDD:464214	22/110 (20%)