DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1703 and CG9281

DIOPT Version :9

Sequence 1:	NP_001285130.1	Gene:	CG1703 / 32112	FlyBaseID:	FBgn0030321	Length:	901	Species:	Drosophila melanogaster
Sequence 2:	NP_001285284.1	Gene:	CG9281 / 32508	FlyBaseID:	FBgn0030672	Length:	611	Species:	Drosophila melanogaster

Alignment Length:	679	Identity:	240/679 - (35%)
Similarity:	370/679 - (54%)	Gaps:	90/679 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 NKAAKESKKEQQKQPEKEVEEQKVEQVLSEKVAAVSLKEKTPEPVPKAEPEPESEPQPDEEADAE 279
            :.|||  |:|.||  :|:...:|::|:.|.|               ||...||.|...:|:..|:
  Fly     2 SSAAK--KREAQK--KKDARNKKIQQIPSTK---------------KANGVPERELTEEEKLCAK 47

  Fly   280 VDSKFEESKEAKEKKLTHKEKKKQKKQQEYERQMELMTKKGGAGHSDLDNNFTMSQVQKSAGQKA 344
            ::.:...|.||:                                              ...|..|
  Fly    48 LEEEARISAEAR----------------------------------------------SCTGSLA 66

  Fly   345 ALEQAVDIKIENFTISAKGNDLFVNANLLIAHGRRYGLVGPNGHGKTTLLRHIATRAFAIPPNID 409
            ...::.|:||.||:|:..|::|..:..|.:..||||||:|.||.||::||..:..|...:||:||
  Fly    67 VHPRSRDVKIANFSITFFGSELLQDTMLELNCGRRYGLIGLNGCGKSSLLAVLGGREVPVPPHID 131

  Fly   410 VLLCEQEVVATDKTAINTILEADVRRTEMLKKADELEKQFVAGDLTVQEELNDTFAELKAIGAYS 474
            :....:|:.|:.|:|:..::|.|..|.::.|.|:||.   ::.:...||:|.|.:..|..:.|..
  Fly   132 IFHLTREIPASSKSALQCVMEVDEERIKLEKLAEELA---MSEEDDAQEQLIDIYERLDDMSADL 193

  Fly   475 AEARARRILAGLGFSKEMQDRPTNKFSGGWRMRVSLARALYLEPTLLMLDEPTNHLDLNAVIWLD 539
            ||.:|.|||.||||.|.||.:....||||||||::|||||:::|.||:||||||||||:|.:||:
  Fly   194 AEVKAARILHGLGFDKAMQQKQAKDFSGGWRMRIALARALFVKPHLLLLDEPTNHLDLDACVWLE 258

  Fly   540 NYLQGWKKTLLIVSHDQSFLDNVCNEIIHLDQKKLQYYKGNYSMFKKMYVQKRREMIKEYEKQEK 604
            ..|:.:|:.|:::||.|.||:.||..||||..|:|:||.|||..|.:..::.....:|:|..::.
  Fly   259 EELKTYKRILVLISHSQDFLNGVCTNIIHLTGKRLKYYTGNYEAFVRTRMELLENQMKQYNWEQD 323

  Fly   605 RLRELK------AHGQSKKAAEKKQKESLTRKQEKNKSKQQKQDEDEGPQELLARPKEYIVKFRF 663
            ::..:|      .||.:|.|.:.:.||....|.......::..|:.             ::.|.|
  Fly   324 QISHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVSDDK-------------VLNFYF 375

  Fly   664 PEPSQLQPPILGVHNVTFAFPSQKP-LFIKVDFGIDLTSRVAIVGPNGVGKSTFLKLLLGELEPQ 727
            |...::.||::.|.||.|.:..:.| ::..::|||||.:|:|:|||||.||||.||||.|:|.|.
  Fly   376 PSCGKVPPPVIMVQNVNFRYNDETPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPT 440

  Fly   728 EGEQRKNHRLHVGRFDQHSGEHLTAEESAAEYLQRLFNLPHEK--ARKALGSFGLVSHAHTIKMK 790
            .|..|||..|.:.|:.||..|.|..:.|..||:.|.|....||  .||.:|.:||........::
  Fly   441 SGMIRKNSHLRIARYHQHLHELLDLDASPLEYMMRAFPDVKEKEEMRKIIGRYGLTGRQQVCPIR 505

  Fly   791 DLSGGQKARVALAELCLSAPDVLILDEPTNNLDIESIDALAEAINEYEGGVIIVSHDERLIRETG 855
            .||.||:.||..|.|....|.:|:||||||:||:|:|||||:|||:::||:::||||.|||.:..
  Fly   506 QLSDGQRCRVVFAWLAWQVPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRLINQVA 570

  Fly   856 CTLYVIEDQTINEIVGEFDDYRKEVLDSL 884
            ..::|.|.:|:.:..|...||:..:.:.:
  Fly   571 EEIWVCEKETVTKWKGGILDYKDHLKNKI 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1703	NP_001285130.1	Uup	351..879	CDD:223562	216/536 (40%)
		ABCF_EF-3	352..573	CDD:213188	99/220 (45%)
		ABC_tran_Xtn	567..>611	CDD:289608	14/49 (29%)
		ABCF_EF-3	676..865	CDD:213188	88/191 (46%)
CG9281	NP_001285284.1	Uup	71..597	CDD:223562	216/541 (40%)
		ABCF_EF-3	74..292	CDD:213188	99/220 (45%)
		ABC_tran_Xtn	286..373	CDD:289608	22/99 (22%)
		ABCF_EF-3	386..578	CDD:213188	87/191 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445833
Domainoid	1	1.000	108	1.000	Domainoid score	I313
eggNOG	1	0.900	-	-		E1_COG0488
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	356	1.000	Inparanoid score	I60
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51340
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19211
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900