DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1703 and abcf-3

DIOPT Version :9

Sequence 1:	NP_001285130.1	Gene:	CG1703 / 32112	FlyBaseID:	FBgn0030321	Length:	901	Species:	Drosophila melanogaster
Sequence 2:	NP_498339.1	Gene:	abcf-3 / 175873	WormBaseID:	WBGene00018339	Length:	712	Species:	Caenorhabditis elegans

Alignment Length:	700	Identity:	252/700 - (36%)
Similarity:	383/700 - (54%)	Gaps:	82/700 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 DDLPNDSEEEEKEQLSNKAAKESKKEQQKQPEKEVEEQKVEQVLSEKVAAVSLKEKTPEPVPK-- 261
            |:||...:::|          .:.|..::..:...|.|..|.:  :.:..|..:: ||..|.|
Worm    77 DNLPKAIKQQE----------ATTKRLEQTVDMAAENQNFEAL--QSIWKVQTRD-TPTTVDKKK 128

  Fly   262 -AEPEPESEPQPDEEADAEVDSKFEESKEAKEKKLTHKEKKKQKKQQEYERQMELMTKKGGAGHS 325
             |:.|..:..:.:..|||.|                  |:||:|.:.
Worm   129 LAKAEDRAAAKAEARADAPV------------------ERKKKKNEP------------------ 157

  Fly   326 DLDNNFTMSQVQ-KSAGQKAALEQAVDIKIENFTISAKGNDLFVNANLLIAHGRRYGLVGPNGHG 389
                :.|.||.. :.:|.:.|  .:.|||:|:..||.....|...|::.:|.||||||||.||.|
Worm   158 ----SATASQAPIRDSGARGA--NSKDIKLESVDISIGTKQLLSCADVTMAFGRRYGLVGRNGIG 216

  Fly   390 KTTLLRHIATRAFAIPPNIDVLLCEQEVVATDKTAINTILEADVRRTEMLKKADELEKQFVAGDL 454
            |||||:.|:::...||..|.:|..||||...|...::.:|.:|.:|..:|.:...|:.:....::
Worm   217 KTTLLKMISSQQLKIPAGISMLSVEQEVEGDDTLVLDAVLMSDTKRQTLLDREKTLQSRINKDNI 281

  Fly   455 TVQE------ELNDTFAELKAIGAYSAEARARRILAGLGFSKEMQDRPTNKFSGGWRMRVSLARA 513
            ...|      ||:..:.|::|:....|.|||..:|.||||:.:.|.|||.:|||||||||:||||
Worm   282 NDAEKTKWNDELSKLYIEMEALQLDKAPARASSLLYGLGFTPDEQKRPTKEFSGGWRMRVALARA 346

  Fly   514 LYLEPTLLMLDEPTNHLDLNAVIWLDNYLQGWKKTLLIVSHDQSFLDNVCNEIIHLDQKKLQYYK 578
            |:::|.||:||||||.||:.||.||:.:||||:.|:|.||||:.||:.:|.:|:||..::|.:||
Worm   347 LFVKPDLLLLDEPTNMLDMRAVYWLEGHLQGWEGTILTVSHDRKFLNEICTDIVHLHTRRLDHYK 411

  Fly   579 GNYSMFKKMYVQKRREMIKEYEKQEKRLRELKAHGQSKKAAEKKQKESLTRKQEKNKSKQQKQDE 643
            |||..|:|...:|..:..:|||.|:    :|:.|.|  :..:|.:..:......:::.|..::..
Worm   412 GNYDQFEKTMKEKLTQQQREYESQQ----QLRQHTQ--EFIDKFRYNAKRAPMVQSRIKMLEKLP 470

  Fly   644 DEGPQELLARPKEYIVKFRFPEPSQLQPPILGVHNVTFAFPSQKP-LFIKVDFGIDLTSRVAIVG 707
            ...|.||     |..:.|:|||...|..|:|.:..|:|.:....| ||.|::.|....||:.|||
Worm   471 VLLPVEL-----ESDIHFKFPECEVLSNPVLQLDEVSFRYNEDSPYLFRKLNLGTHANSRICIVG 530

  Fly   708 PNGVGKSTFLKLLLGELEPQEGEQRKNHRLHVGRFDQHSGEHLTAEESAAEYLQRLFNLP---HE 769
            .||.||:|.|||||.:|:|..|.:..|.|:.:..|.||..:.|..|.||.|.|.:  |.|   .|
Worm   531 ENGAGKTTLLKLLLDDLQPSVGLRNVNRRIRIAYFTQHHVDQLDMETSAIEVLMK--NHPGKTQE 593

  Fly   770 KARKALGSFGLVSHAHTIKMKDLSGGQKARVALAELCLSAPDVLILDEPTNNLDIESIDALAEAI 834
            ..|.|||.|||........::.||||||:|:|.|.|.|..|:.||||||||:||:|:::||.:|:
Worm   594 DYRAALGRFGLAGDMALQSVETLSGGQKSRLAFANLALMQPNYLILDEPTNHLDVETVEALGKAL 658

  Fly   835 NEYEGGVIIVSHDERLIRETGCTLYVIEDQTINEIVGEFDDYRKEVLDSL 884
            |.:.|||::|||||:||......|:|::|:.:..:.|..::|||:|...|
Worm   659 NVFNGGVVLVSHDEQLIELVCKELWVVKDRMVTTLEGGLEEYRKQVYKQL 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1703	NP_001285130.1	Uup	351..879	CDD:223562	221/537 (41%)
		ABCF_EF-3	352..573	CDD:213188	102/226 (45%)
		ABC_tran_Xtn	567..>611	CDD:289608	16/43 (37%)
		ABCF_EF-3	676..865	CDD:213188	86/192 (45%)
abcf-3	NP_498339.1	PLN03073	22..702	CDD:215558	248/692 (36%)
		ABCF_EF-3	179..406	CDD:213188	102/226 (45%)
		ABC_tran_Xtn	400..483	CDD:289608	24/93 (26%)
		ABCF_EF-3	496..688	CDD:213188	86/193 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830