Protein Alignment CG1703 and ABCF2-H2BK1

DIOPT Version :10

• Sequence 1: NP_572736.1
• Gene: CG1703 / 32112
• FlyBaseID: FBgn0030321
• Length: 901
• Species: Drosophila melanogaster
• Sequence 2: NP_005683.2
• Gene: ABCF2-H2BK1 / 114483834
• HGNCID: 54751
• Length: 634
• Species: Homo sapiens
• Alignment Length: 656
• Identity: 244/656 - (37%)
• Similarity: 368/656 - (56%)
• Gaps: 64/656 - (9%)

  Fly   242 LSEKVAAVSLKEKTPEPVPKAEPEPESEPQPDEEADAEVDSKFEESKEAKEKKLTHKEKKKQKKQ 306
            |::|.||   |:|   ...||...|..  ..:|..|...:.:..|..||..::.|
Human     5 LAKKKAA---KKK---EAAKARQRPRK--GHEENGDVVTEPQVAEKNEANGRETT---------- 51

  Fly   307 QEYERQMELMTKKGGAGHSDLDNNFTMSQVQKSA--GQKAALEQAVDIKIENFTISAKGNDLFVN 369
                 :::|:||       :|: :|.|.:....|  |..|:...:.|:.|.|.:::..|.:|..:
Human    52 -----EVDLLTK-------ELE-DFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSD 103

  Fly   370 ANLLIAHGRRYGLVGPNGHGKTTLLRHIATRAFAIPPNIDVLLCEQEVVATDKTAINTILEADVR 434
            ..|.:..||||||:|.||.||:.||..|..|...||.:||:....:|:..:|||.::.::|.|..
Human   104 TKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTE 168

  Fly   435 RTEMLKKADELEKQFVAGDLTVQEELNDTFAELKAIGAYSAEARARRILAGLGFSKEMQDRPTNK 499
            |..:.|:|:.|     |.:....|:|.:.:..|:.:.|..||.||.|||.||||:..||.:....
Human   169 RAMLEKEAERL-----AHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKD 228

  Fly   500 FSGGWRMRVSLARALYLEPTLLMLDEPTNHLDLNAVIWLDNYLQGWKKTLLIVSHDQSFLDNVCN 564
            |||||||||:|||||::.|.:|:||||||||||:|.:||:..|:.:|:.|::|||.|.||:.||.
Human   229 FSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCT 293

  Fly   565 EIIHLDQKKLQYYKGNYSMFKKMYVQKRREMIKEYEKQEKRLRELK------AHGQSKKAAEKKQ 623
            .|||:..|||:||.|||..:.|..::.....:|.:..::.::..:|      .||.:|.|.:.:.
Human   294 NIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQS 358

  Fly   624 KESLTRKQEKNKSKQQKQDEDEGPQELLARPKEYIVKFRFPEPSQLQPPILGVHNVTFAFPSQKP 688
            ||...:|...:           |..|.:...|  .:.|.||...::.||::.|.||:|.:....|
Human   359 KEKTLQKMMAS-----------GLTERVVSDK--TLSFYFPPCGKIPPPVIMVQNVSFKYTKDGP 410

  Fly   689 -LFIKVDFGIDLTSRVAIVGPNGVGKSTFLKLLLGELEPQEGEQRKNHRLHVGRFDQHSGEHLTA 752
             ::..::|||||.:|||:|||||.||||.||||.|||.|.:|..||:..:.:||:.||..|.|..
Human   411 CIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDL 475

  Fly   753 EESAAEYLQRLFNLPH----EKARKALGSFGLVSHAHTIKMKDLSGGQKARVALAELCLSAPDVL 813
            :.|..||:.:.:  |.    |:.||.:|.:||........:::||.|||.||.||.|....|.:|
Human   476 DLSPLEYMMKCY--PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 538

  Fly   814 ILDEPTNNLDIESIDALAEAINEYEGGVIIVSHDERLIRETGCTLYVIEDQTINEIVGEFDDYRK 878
            .||||||:||||:|||||:||||:|||:::||||.|||::....::|.|.|||.:..|:...|::
Human   539 FLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKE 603

  Fly   879 EVLDSL 884
            .:...|
Human   604 HLKSKL 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1703	NP_572736.1	Uup	354..878	CDD:440254	218/534 (41%)
ABCF2-H2BK1	NP_005683.2	Uup	90..604	CDD:440254	217/533 (41%)