DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1703 and abcf1

DIOPT Version :9

Sequence 1:	NP_001285130.1	Gene:	CG1703 / 32112	FlyBaseID:	FBgn0030321	Length:	901	Species:	Drosophila melanogaster
Sequence 2:	XP_002939514.2	Gene:	abcf1 / 100490104	XenbaseID:	XB-GENE-993168	Length:	884	Species:	Xenopus tropicalis

Alignment Length:	929	Identity:	467/929 - (50%)
Similarity:	608/929 - (65%)	Gaps:	93/929 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KGKKKERFDDDEEQLEKVQEKKPPTSKKGGKKGKRGGGGGDSSDEDVTTRNRDNEDLESIASSNQ 69
            :|.|.|..:::||     :|.|...::|..||||:...|..|..|:::..|:..::.|:.....:
Frog     3 RGGKHEVGEEEEE-----EEVKGKETEKVVKKGKKDKKGKKSFFEELSADNKQAQEEEAAKEREK 62

  Fly    70 SK---QQTAGKKQAKKGKKGKRNNDWSDEDEKPEK----------SLPANDLDDEDDDEAPLASK 121
            .|   ||...|::.||..:.|:..|..|:||:.::          |:.|:|.|:|.|      .|
Frog    63 EKELQQQQQKKREKKKKDRRKQKGDEDDDDEEKKEREIAERLKKLSVQASDEDEEPD------VK 121

  Fly   122 PAAKKPQPSKKNKKN--KKKNDDFSDEDKPELDLDDLDNEEDEVEVVAVKPASKKSKKKQQAQQK 184
            ||   |:..||...|  ....:|.||:::.|   :.:.|:.||         .|:||.|:..:.|
Frog   122 PA---PKAGKKQGSNIFAALVEDQSDDEEEE---EQVSNQVDE---------KKQSKGKKNVKGK 171

  Fly   185 NMFAMSDDEEDEVADDLPND---------------SEEEEKEQLSNKAAKESKK----------E 224
            :   .:.:|..|..:|:|.:               .|:|:|.:..||.:|.|:|          :
Frog   172 H---KAPEERPESEEDIPKEKSKGKKPVPSAASVNEEDEKKTEKGNKKSKPSQKPVSKAASVESD 233

  Fly   225 QQKQPEKEVEEQKVEQVLSEKVAAVSLKEKTPEPVPKAEPEPESEPQPDEEADAEVDSKFEESKE 289
            ::|:|||..::.|..|   .:..|:.::|   :.|.....|...:....|:.....:..|
Frog   234 EEKKPEKGSKKTKPSQ---NRFGALDIEE---DHVSGGSKEGSGDEGETEDKTTAAEDPF----- 287

  Fly   290 AKEKKLTHKEKKKQKKQQEYERQMELMTKKGGAGHSDLDNNFTMSQVQKSAGQKAALEQAVDIKI 354
               ..|:.|||||:||..|||:|:..|.|...|     :|:|::||.:.|:.| |.||.|.||||
Frog   288 ---ANLSKKEKKKKKKMLEYEKQVATMKKITAA-----ENDFSVSQAELSSRQ-AMLENASDIKI 343

  Fly   355 ENFTISAKGNDLFVNANLLIAHGRRYGLVGPNGHGKTTLLRHIATRAFAIPPNIDVLLCEQEVVA 419
            |.|:|||.|.:|||||:|.:..|||||||||||.||||||:|||.:|..||||||||||||||||
Frog   344 EKFSISAHGKELFVNADLYVVAGRRYGLVGPNGKGKTTLLKHIANKALNIPPNIDVLLCEQEVVA 408

  Fly   420 TDKTAINTILEADVRRTEMLKKADELEKQFVAGDLTVQEELNDTFAELKAIGAYSAEARARRILA 484
            .|..|:..:|:||.:|.::|::..:|:.:...||....|.|...:.||:|:||.||||:||||||
Frog   409 DDTPAVQAVLKADKKRLKLLEEERKLQTRLEKGDDNAAERLEKVYEELRAMGAASAEAKARRILA 473

  Fly   485 GLGFSKEMQDRPTNKFSGGWRMRVSLARALYLEPTLLMLDEPTNHLDLNAVIWLDNYLQGWKKTL 549
            ||||:.|||||.|.:|||||||||||||||::||||||||||||||||||||||:||||||||||
Frog   474 GLGFTPEMQDRETRRFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWKKTL 538

  Fly   550 LIVSHDQSFLDNVCNEIIHLDQKKLQYYKGNYSMFKKMYVQKRREMIKEYEKQEKRLRELKAHGQ 614
            |||||||.|||:||.:|:|||.:||.||:|||..|||||.||::|:.|:|:||||:|::|||.|:
Frog   539 LIVSHDQGFLDDVCTDIMHLDSQKLYYYRGNYMTFKKMYQQKQKELQKQYDKQEKKLKDLKAGGK 603

  Fly   615 SKKAAEKKQKESLTRKQEK-NKSKQQKQDEDEGPQELLARPKEYIVKFRFPEPSQLQPPILGVHN 678
            |.|.|||:.||:|||||:| .|....|:|.|  |.|||.|||||.|||.||.|..|.|||||:|.
Frog   604 SAKQAEKQTKEALTRKQQKCQKKNNDKEDND--PVELLKRPKEYTVKFTFPNPPPLSPPILGLHG 666

  Fly   679 VTFAFPSQKPLFIKVDFGIDLTSRVAIVGPNGVGKSTFLKLLLGELEPQEGEQRKNHRLHVGRFD 743
            |.|.:..|||||..:|||||:.|||.|||||||||||.|.||.|:|.|.:||.||||||.:|.|:
Frog   667 VDFCYSGQKPLFKNLDFGIDMDSRVCIVGPNGVGKSTLLLLLTGKLTPTKGEMRKNHRLKIGFFN 731

  Fly   744 QHSGEHLTAEESAAEYLQRLFNLPHEKARKALGSFGLVSHAHTIKMKDLSGGQKARVALAELCLS 808
            |...:.|..||:|.|||||.||||::.|||.||.|||.||||||::..|||||||||..||||..
Frog   732 QQYADQLNMEETATEYLQRNFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELCCR 796

  Fly   809 APDVLILDEPTNNLDIESIDALAEAINEYEGGVIIVSHDERLIRETGCTLYVIEDQTINEIVGEF 873
            .||||||||||||||||||||||||:|||:|.||.||||.|||.||.|.|:|:||||:|:|.|:|
Frog   797 EPDVLILDEPTNNLDIESIDALAEAVNEYKGAVITVSHDARLITETNCHLWVVEDQTVNQIEGDF 861

  Fly   874 DDYRKEVLDSLGEV-VNNP 891
            |||::|||:||||| ||.|
Frog   862 DDYKREVLESLGEVIVNKP 880

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1703	NP_001285130.1	Uup	351..879	CDD:223562	354/528 (67%)
		ABCF_EF-3	352..573	CDD:213188	152/220 (69%)
		ABC_tran_Xtn	567..>611	CDD:289608	26/43 (60%)
		ABCF_EF-3	676..865	CDD:213188	128/188 (68%)
abcf1	XP_002939514.2	LYRIC	<157..>251	CDD:374019	25/108 (23%)
abcf1	XP_002939514.2	Uup	339..870	CDD:223562	356/532 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2751
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H849
Inparanoid	1	1.050	822	1.000	Inparanoid score	I460
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	1	1.000	-	-		FOG0006074
OrthoInspector	1	1.000	-	-		oto102466
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4371
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060