DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1703 and abcf3

DIOPT Version :9

Sequence 1:	NP_001285130.1	Gene:	CG1703 / 32112	FlyBaseID:	FBgn0030321	Length:	901	Species:	Drosophila melanogaster
Sequence 2:	XP_017206710.1	Gene:	abcf3 / 100331227	ZFINID:	ZDB-GENE-050517-32	Length:	710	Species:	Danio rerio

Alignment Length:	737	Identity:	270/737 - (36%)
Similarity:	389/737 - (52%)	Gaps:	92/737 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 KNMFAMSDDEEDE----VADDLPNDSEEEEK---------EQLSNK-----------------AA 218
            ||.|...|.|..|    |.|...:|.|:.|:         :::.:|                 ..
Zfish    10 KNEFPQIDSELFEYITGVLDSGGSDFEDAEEVFDAIGGFLQEVGDKNEDDIRNICFQMFNTLQLT 74

  Fly   219 KESKKEQQKQPEKEVEEQKVEQVLSEKVAAVSLKEKTPEPVPKAEPEPESEPQPDEEADAEVDSK 283
            |....:||...|..|:   :.||.::  ||.|:.:.....:.|..|            ...||:|
Zfish    75 KCDSGQQQVLLEAPVQ---LSQVSAD--AASSVNDVHGIWMVKRNP------------GTTVDAK 122

  Fly   284 FEESKEAKEKKLTHKEKKKQKKQQEYERQMELMTKKGGAGHSDLDNNFTMSQVQKSAGQKAALEQ 348
            ..|..|||.|  ...|::.:|..|:...|:.|.........|..:|....|...:|
Zfish   123 KLEKAEAKLK--AKHERRNEKDSQKSSSQLVLEEASASQASSKKENRVDSSGKNRS--------- 176

  Fly   349 AVDIKIENFTISAKGNDLFVNANLLIAHGRRYGLVGPNGHGKTTLLRHIATRAFAIPPNIDVLLC 413
             .||:||||.:|.....|...|.|.:|.||||||||.||.||||||:.:|:|:..:|.:|.:|..
Zfish   177 -YDIRIENFDVSFGERCLLQGAELCLASGRRYGLVGRNGLGKTTLLKMLASRSLRVPLHISILHV 240

  Fly   414 EQEVVATDKTAINTILEADVRRTEMLKKADELEKQFVAGDLTVQE--ELNDTFAELKAIGAYSAE 476
            ||||...:..|:.::||:|..|.|:||:...|......|.....|  .|::.:|:|:.|.|..|.
Zfish   241 EQEVDGDETLALQSVLESDTLREELLKEERRLNTHIANGTAEGLESVRLSEVYAKLEEIEADKAP 305

  Fly   477 ARARRILAGLGFSKEMQDRPTNKFSGGWRMRVSLARALYLEPTLLMLDEPTNHLDLNAVIWLDNY 541
            |||..|||||||:.:||.:.|.:||||||||::|||||:..|.||:||||||.||:.|::||:||
Zfish   306 ARASVILAGLGFTSKMQQQATKEFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENY 370

  Fly   542 LQGWKKTLLIVSHDQSFLDNVCNEIIHLDQKKLQYYKGNYSMFKKMYVQKRREMIKEYEKQEKRL 606
            ||.|:.|:|:||||::||:.|..::|||..::|:.|:|:|..|.|....:.:...:|||.|
Zfish   371 LQTWQSTILVVSHDRNFLNAVVTDVIHLHSQRLESYRGDYENFIKTKEDRLKNQQREYEAQ---- 431

  Fly   607 RELKAHGQ---------SKKAAEKKQKESLTRKQEKNKSKQQKQDEDEGPQELLARPKEYIVKFR 662
            .:.:.|.|         :.:||:.:.|..|..|.                .||....||..|..|
Zfish   432 LQYREHIQVFIDRFRYNANRAAQVQSKLKLLEKL----------------PELKPMVKESEVALR 480

  Fly   663 FPEP-SQLQPPILGVHNVTFAFPSQKPLFIKVDFGIDLTSRVAIVGPNGVGKSTFLKLLLGELEP 726
            ||:. .:|.||||.:..|.|.:..::.||..:....||.||:.|||.||.||||.||||:|||.|
Zfish   481 FPDNFEKLSPPILQLDEVEFGYSPEQRLFSGLCISADLESRICIVGENGAGKSTLLKLLMGELTP 545

  Fly   727 QEGEQRKNHRLHVGRFDQHSGEHLTAEESAAEYLQRLF-NLPHEKARKALGSFGLVSHAHTIKMK 790
            ..|.:..:.:|.:|.|.||..:.|.....:.|.|.:.| ....|:.|..||.:|:.....|..:.
Zfish   546 LGGARHAHRKLKIGYFSQHHVDQLDLNVCSIELLLKRFPGETEEEYRHQLGRYGITGELATRPVA 610

  Fly   791 DLSGGQKARVALAELCLSAPDVLILDEPTNNLDIESIDALAEAINEYEGGVIIVSHDERLIRETG 855
            .||||||:|||.|::.:..|:..|||||||:||:|:|:|||:|:|:::|||::|||||||||...
Zfish   611 SLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALAKALNKFKGGVVLVSHDERLIRMVC 675

  Fly   856 CTLYVIEDQTINEIVGEFDDYR 877
            ..|:|.|...::.|.|.||:||
Zfish   676 KELWVCEAGRVHRIDGGFDEYR 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1703	NP_001285130.1	Uup	351..879	CDD:223562	229/540 (42%)
		ABCF_EF-3	352..573	CDD:213188	109/222 (49%)
		ABC_tran_Xtn	567..>611	CDD:289608	13/43 (30%)
		ABCF_EF-3	676..865	CDD:213188	83/189 (44%)
abcf3	XP_017206710.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820