Protein Alignment rho-4 and RHBDL1

DIOPT Version :9

• Sequence 1: NP_525084.1
• Gene: rho-4 / 32109
• FlyBaseID: FBgn0030318
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: XP_024306253.1
• Gene: RHBDL1 / 9028
• HGNCID: 10007
• Length: 526
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 84/314 - (26%)
• Similarity: 126/314 - (40%)
• Gaps: 74/314 - (23%)

  Fly     3 VKTVNRQQSQT-PAQQLQLQQQRDVENGLYPTIPAERRS--------------PPSRPQTLRQDT 52
            :|...|:|:.| |..|...:.:.|..:...|.:.:..|:              .|.....:..||
Human    28 IKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADT 92

  Fly    53 ----IDMEEIPLNQTNSQEPEDRRKMHEIFDKHDSDRDGLINTHELKELISDGYCRDIPAYIAD- 112
                :...|:||         |..|:..:.....|:..|.:...||.:|||..........||:
Human    93 FTGLVHSHELPL---------DPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANG 148

  Fly   113 -QILKRSDQDNDGHLDFEEFYAMSLRHKWMVRNMLTRYCRYVVPPPKPLEGDEPDGAYEKQMSIC 176
             :.|.|     ||.||....            .:..|:.|||.....|.|.|.....|..:.  |
Human   149 QRALPR-----DGPLDEPGL------------GVYKRFVRYVAYEILPCEVDRRWYFYRHRS--C 194

  Fly   177 PPPLTMVLFSIIEIIMFL----------VDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYE 231
            |||:.|...::.:||:||          :...|    |.|.       ..|    .:|:|..|..
Human   195 PPPVFMASVTLAQIIVFLCYGARLNKWVLQTYH----PEYM-------KSP----LVYHPGHRAR 244

  Fly   232 GWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMG 285
            .|||::|||:|||:..|..|.::|:.:|:.||:||...|:.|:||||||||..|
Human   245 AWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGEAG 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	37/151 (25%)
		EFh	73..134	CDD:238008	16/62 (26%)
		Rhomboid	226..374	CDD:396315	30/60 (50%)
RHBDL1	XP_024306253.1	Rhomboid	239..>295	CDD:328780	27/55 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.880