DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and RBL5

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_175667.1	Gene:	RBL5 / 841690	AraportID:	AT1G52580	Length:	309	Species:	Arabidopsis thaliana

Alignment Length:	251	Identity:	58/251 - (23%)
Similarity:	102/251 - (40%)	Gaps:	46/251 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 PPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFL--VDVIHFQDDPNYQDR------IG 211
            |.|..:|...|..|........|.|....|..:|....|:  ...::..|.|...|.      :|
plant     6 PIPPDIENGPPPPARPHFRPPIPVPWVAWLVPLILAANFVTFATTMYVNDCPARSDECLLFDVLG 70

  Fly   212 ESTSGPAATLFIYNP---------------YKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIA 261
            ..:..|.....:..|               .:..|.||.:|.:::|.|.:|||.|:|..:.:|:.
plant    71 RLSFQPIKENMLLGPSIPTLRKLGALERRLVEEGERWRLISCIWLHGGFLHLMANMISLMCIGMR 135

  Fly   262 LELVHHWWRVGLVYLAGVLAGSMGTSLT---SPRIFLAGASGGVYALITAHIATIIMNYSEMEYA 323
            ||....:.|:|.:|:...|.||:.:.||   ..|:.: ||||.::.|:.|.::.:|.|::..|..
plant   136 LEQEFGFMRIGALYVISGLGGSLVSCLTDSQGERVSV-GASGALFGLLGAMLSELITNWTIYENK 199

  Fly   324 IVQLLAFLVFCFTDLGTSVYRHLTDQHDQIGYV------AHLSGAVAGLLVGIGVL 373
            ...|:..::....:|             .:|::      ||..|.:||..:|..:|
plant   200 CTALMTLILIIVLNL-------------SVGFLPRVDNSAHFGGFLAGFFLGFVLL 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	10/43 (23%)
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	43/172 (25%)
RBL5	NP_175667.1	Rhomboid	104..246	CDD:366759	42/153 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1037
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.780