DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and RBL6

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001184975.1	Gene:	RBL6 / 837831	AraportID:	AT1G12750	Length:	307	Species:	Arabidopsis thaliana

Alignment Length:	193	Identity:	50/193 - (25%)
Similarity:	92/193 - (47%)	Gaps:	28/193 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 EGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFL 295
            |.||.::.|::|.||:||:||:...|..||.||....:.|:||:||.....||:.::|...:...
plant    96 EKWRLITAMWLHAGIIHLVMNMFDVIIFGIRLEQQFGFIRIGLIYLISGFGGSILSALFLQKSIS 160

  Fly   296 AGASGGVYALITAHIATIIMNYSEMEYAIVQLLAFLVFCFTDLGTSVYRHLTDQHDQIGYVAHLS 360
            .||||.:..|:.|.::.::.|::..:..:..||:||.....:|...:.       ..:...||:.
plant   161 VGASGALLGLMGAMLSELLTNWTIYKSKLCALLSFLFIIAINLAIGLL-------PWVDNFAHIG 218

  Fly   361 GAVAGLLVGIGVLRNLEVRRWER--------------------ILWWVAVIVYFALMTTGIII 403
            |.:.|..:|..:|...: ..||.                    :|::||.::..|.:|.|:::
plant   219 GLLTGFCLGFILLMQPQ-SGWEEFRNSSQYGARARSKYNPCQYVLFFVAAVLVVAGLTVGLVM 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	41/142 (29%)
RBL6	NP_001184975.1	Rhomboid	92..232	CDD:279958	41/142 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1037
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.780