DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and RBL3

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_196342.1	Gene:	RBL3 / 830616	AraportID:	AT5G07250	Length:	346	Species:	Arabidopsis thaliana

Alignment Length:	296	Identity:	61/296 - (20%)
Similarity:	121/296 - (40%)	Gaps:	79/296 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 ICPPPLTMVL----------------------FSIIEIIMFLVDVIHFQDDPNYQDR-------- 209
            |.||||.:.|                      |.:..:.:|:| .:...:.||:.:.
plant    29 IGPPPLPVALSSSTEFGDNALSSRWTSWLVPMFVVANVAVFVV-AMFVNNCPNHFESHRLRGHCV 92

  Fly   210 ---IGESTSGPAATLFIYNP----------------YKRYEGWRFVSYMFVHVGIMHLMMNLIIQ 255
               :|..:..|..|..::.|                .::.||||.::.:::|.|::||..|::..
plant    93 AKFLGRLSFEPLRTNPLFGPSSHTLEKLGALEWSKVVEKKEGWRLLTCIWLHAGVIHLGANMLSL 157

  Fly   256 IFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEM 320
            :|:||.||....:.|:|::||...:.||:.:||........||||.::.|:.:.::.:..|::..
plant   158 VFIGIRLEQQFGFVRIGVIYLLSGIGGSVLSSLFIRNSISVGASGALFGLLGSMLSELFTNWTIY 222

  Fly   321 EYAIVQLLAFLVFCFTDLGTSVYRHLTDQHDQIGYVAHLSGAVAGLLVGI--------------- 370
            ...|..||..|.....:|...:..|:.:       .||:.|.|.|.|:|.
plant   223 SNKIAALLTLLFVILINLAIGILPHVDN-------FAHVGGFVTGFLLGFILLARPQFKWLAREH 280

  Fly   371 ---GVLRNLEVRRWERILWWVAVIVYFALMTTGIII 403
               |.....:.:.::.:||.::::    |:..|.::
plant   281 MPQGTPLRYKYKTYQYLLWLLSLV----LLIAGFVV 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	9/43 (21%)
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	43/181 (24%)
RBL3	NP_196342.1	Rhomboid	128..269	CDD:396315	41/147 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1037
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.780