DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and RBL7

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_194038.1	Gene:	RBL7 / 828406	AraportID:	AT4G23070	Length:	313	Species:	Arabidopsis thaliana

Alignment Length:	261	Identity:	63/261 - (24%)
Similarity:	115/261 - (44%)	Gaps:	56/261 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 IIEIIMFLVDVIHFQDDPNYQDR-------------------IGESTS-----GPAATLFIYNPY 227
            |..:::|:| |:::.|.|:...|                   :|.|:|     |..|...|.  :
plant    39 IANVVVFVV-VMYYNDCPHKSHRCLAKFLGRFSFESFKSNPLLGPSSSTLEKMGALAWGKIV--H 100

  Fly   228 KRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPR 292
            || :.||.::.|::|.|::||:.|:....::|:.||....:.|||.:||.....||:.:.|....
plant   101 KR-QVWRLLTCMWLHAGVIHLLANMCCVAYIGVRLEQQFGFVRVGTIYLVSGFCGSILSCLFLED 164

  Fly   293 IFLAGASGGVYALITAHIATIIMNYSEMEYAIVQLLAFLVFCFTDLGTSVYRHLTDQHDQIGYVA 357
            ....|||..::.|:.|.::.:::|::..:...|.::..||....:||....       ..:...|
plant   165 AISVGASSALFGLLGAMLSELLINWTTYDNKGVAIVMLLVIVGVNLGLGTL-------PPVDNFA 222

  Fly   358 HLSGAVAGLLVGIGVLRNLEVRRWER--------------------ILWWVAVIVYFALMTTGII 402
            |:.|...|.|:|..:|.:.:. .||.                    :|..||.||:.|..|:|::
plant   223 HIGGFFGGFLLGFLLLIHPQF-EWEENQVSLMPGTIVKPKYNTCQLVLCIVASIVFVAGFTSGLV 286

  Fly   403 I 403
            |
plant   287 I 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	3/9 (33%)
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	38/147 (26%)
RBL7	NP_194038.1	Rhomboid	98..224	CDD:396315	34/135 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1037
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.780