DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and parl

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	XP_021322181.1	Gene:	parl / 792889	-ID:	-	Length:	361	Species:	Danio rerio

Alignment Length:	181	Identity:	39/181 - (21%)
Similarity:	63/181 - (34%)	Gaps:	69/181 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 FIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLII--------------QIFLGIALELVHHWWRVG 272
            |..||..:...|..:...|.|..:.||..|:.:              :.|:.:.|.       .|
Zfish   177 FTSNPSSKALCWPMLLSTFSHYSLFHLSANMYVLWSFSSSIINMMGKEQFMALYLS-------TG 234

  Fly   273 LV-----YLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEMEYAIVQLLAFL- 331
            ::     |::....|.:|.||        ||||.:.|:    :|.:.....|.:.||:    ||
Zfish   235 VISTFVSYVSKTAMGRLGPSL--------GASGAIMAV----LAAVCTKMPEAKLAII----FLP 283

  Fly   332 VFCFTD----------------LGTSVYRHLTDQHDQIGYVAHLSGAVAGL 366
            ::.||.                ||...:.|          .|||.||:.|:
Zfish   284 MYTFTAGNALKAIVALDTTGLILGWRFFDH----------AAHLGGALFGI 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	37/177 (21%)
parl	XP_021322181.1	Rhomboid	188..335	CDD:307698	36/170 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900