DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and rhbdf1b

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	XP_021328201.1	Gene:	rhbdf1b / 563403	ZFINID:	ZDB-GENE-130531-6	Length:	894	Species:	Danio rerio

Alignment Length:	267	Identity:	43/267 - (16%)
Similarity:	100/267 - (37%)	Gaps:	61/267 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 YCRYVVPPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFLVDVIHFQDDPNYQDRIGES 213
            ||.::            .|.:.::.::|                   ..:|..||
Zfish   653 YCDFM------------KGYFHEEATLC-------------------SQVHCMDD---------- 676

  Fly   214 TSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAG 278
               ....|...||....:.:|....:|:|.||:|.::::..|:.:...||.:..|.|:.::|:..
Zfish   677 ---VCGLLPFLNPEIPDQFYRLWLSLFLHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILS 738

  Fly   279 VLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEME---YAIVQLLAFLVFCFTDLGT 340
            .:.|::.:::..|.....|.:|..:.::......:..::..:.   .|..:|...::|.|. .|.
Zfish   739 GITGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFTKLSCVVLFLFA-FGL 802

  Fly   341 SVYRHLTDQHDQIGYVAHLSGAVAGLLVGIGVLRNLEVRRWE----RILWWVAVIVYFALMTTGI 401
            ..:         |...||:.|.|:|..:....|..:...|.:    |:...||:.::..:.::.:
Zfish   803 LPW---------IDNFAHICGFVSGFFLSFAFLPYISFGRMDMYRKRLQILVALTLFVGIFSSFV 858

  Fly   402 IIHVFVP 408
            ::....|
Zfish   859 VLFYVYP 865

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	4/47 (9%)
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	28/150 (19%)
rhbdf1b	XP_021328201.1	Rhomboid_SP	130..348	CDD:315299
rhbdf1b	XP_021328201.1	Rhomboid	686..829	CDD:307698	29/152 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920