DRSC/TRiP Functional Genomics Resources

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Protein Alignment rho-4 and PARL

DIOPT Version :9

Sequence 1:NP_525084.1 Gene:rho-4 / 32109 FlyBaseID:FBgn0030318 Length:417 Species:Drosophila melanogaster
Sequence 2:XP_005247639.1 Gene:PARL / 55486 HGNCID:18253 Length:394 Species:Homo sapiens


Alignment Length:190 Identity:42/190 - (22%)
Similarity:66/190 - (34%) Gaps:78/190 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 TSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNL---------IIQI-----FLGIALEL 264
            ||.||:.: :.:|        .:...|.|..:.|:..|:         |:.|     |:.:.|. 
Human   197 TSNPASKV-LCSP--------MLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLS- 251

  Fly   265 VHHWWRVGLV-----YLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEMEYAI 324
                  .|::     |:..|..|..|.||        ||||.:..:    :|.:.....|...||
Human   252 ------AGVISNFVSYVGKVATGRYGPSL--------GASGAIMTV----LAAVCTKIPEGRLAI 298

  Fly   325 VQLLAFL-VFCFTD----------------LGTSVYRHLTDQHDQIGYVAHLSGAVAGLL 367
            :    || :|.||.                ||...:.|          .|||.||:.|::
Human   299 I----FLPMFTFTAGNALKAIIAMDTAGMILGWKFFDH----------AAHLGGALFGMI 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rho-4NP_525084.1 EFh_HEF <57..197 CDD:355006
EFh 73..134 CDD:238008
Rhomboid 226..374 CDD:396315 38/178 (21%)
PARLXP_005247639.1 Rhomboid 209..351 CDD:279958 37/169 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0705
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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