DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and rho-7

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001286324.1	Gene:	rho-7 / 36281	FlyBaseID:	FBgn0033672	Length:	351	Species:	Drosophila melanogaster

Alignment Length:	172	Identity:	42/172 - (24%)
Similarity:	63/172 - (36%)	Gaps:	47/172 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 TLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQ--------IFLGIALELVHHWWRVGLVYL 276
            |.|..||..:...|......|.|...|||..|:.:.        :.||....|.        |||
  Fly   173 TYFTSNPAAKVVCWPMFLSTFSHYSAMHLFANMYVMHSFANAAAVSLGKEQFLA--------VYL 229

  Fly   277 -AGVLAGSMGT---SLTSPRIFLAGASGGVYALITAHIATIIMNYSEMEYAI------------- 324
             |||.:..|..   :.||......||||.:..|: |::.|   .|.:.:.:|
  Fly   230 SAGVFSSLMSVLYKAATSQAGMSLGASGAIMTLL-AYVCT---QYPDTQLSILFLPALTFSAGAG 290

  Fly   325 VQLLAFLVFCFTDLGTSVYRHLTDQHDQIGYVAHLSGAVAGL 366
            :::|..:.|....:|...:.|          .|||.||:.|:
  Fly   291 IKVLMGIDFAGVVMGWKFFDH----------AAHLGGAMFGI 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	39/166 (23%)
rho-7	NP_001286324.1	Rhomboid	186..327	CDD:396315	38/159 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900