Protein Alignment rho-4 and Rhbdf2

DIOPT Version :9

• Sequence 1: NP_525084.1
• Gene: rho-4 / 32109
• FlyBaseID: FBgn0030318
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_001100537.2
• Gene: Rhbdf2 / 303690
• RGDID: 1309699
• Length: 825
• Species: Rattus norvegicus
• Alignment Length: 392
• Identity: 69/392 - (17%)
• Similarity: 149/392 - (38%)
• Gaps: 88/392 - (22%)

  Fly    46 QTLRQDTIDMEEIPLNQTNSQEPEDRRKMHEIFDKHDSDRDGLINTHE----LKELISDGYCRDI 106
            |||::|..:.....:...|..||.|:..:.:       .:...:..|:    .:|..|.|
  Rat   480 QTLKKDCSETLATFVKWQNDTEPSDKSDLSQ-------KQPSAVVCHQDPRTCEEPASSG----- 532

  Fly   107 PAYI-ADQILK------RSDQDNDG--HLDFE-EFYAMSLRHKWMVRNMLTRYCRYVVPPPKPLE 161
             |:| .|.|.|      ::..:..|  |:|.: :.....:..|.........||.::
  Rat   533 -AHIWPDDITKWPICTEQAQSNRTGLLHIDCKIKGRPCCIGTKGSCEITTREYCEFM-------- 588

  Fly   162 GDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFLVDVIHFQDDPNYQDRIGESTSGPAATLFIYNP 226
                .|.:.::.::|..  ...|..:..::.||        :|...|:.
  Rat   589 ----HGYFHEEATLCSQ--VHCLDEVCGLLPFL--------NPEIPDQF---------------- 623

  Fly   227 YKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSP 291
               |..|   ..:|:|.||:|.:::::.|:.:...||.:..|.|:.::::...:.|::.:::..|
  Rat   624 ---YRIW---LSLFLHAGIVHCLVSVVFQMTILRDLEKLAGWHRISIIFILSGITGNLASAIFLP 682

  Fly   292 RIFLAGASGGVYALITAHIATIIMNYSEME---YAIVQLLAFLVFCFTDLGTSVYRHLTDQHDQI 353
            .....|.:|..:.|:......:..::..:|   .|...|.|.::|.|          :......|
  Rat   683 YRAEVGPAGSQFGLLACLFVELFQSWQLLERPWKAFFNLSAIVLFLF----------ICGLLPWI 737

  Fly   354 GYVAHLSGAVAGLLVGIGVLRNLEV----RRWERILWWVAVIVYFALMTTGIIIHVFVPDYFPKQ 414
            ..:||:.|.::|:|:....|..:..    |..::.|..|:::|:..|..:.::.....|..:|..
  Rat   738 DNIAHIFGFLSGMLLAFAFLPYITFGTSDRYRKQALILVSLLVFAGLFASLVLWLYIYPINWPWI 802

  Fly   415 EY 416
            ||
  Rat   803 EY 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	24/153 (16%)
		EFh	73..134	CDD:238008	12/74 (16%)
		Rhomboid	226..374	CDD:396315	29/150 (19%)
Rhbdf2	NP_001100537.2	Rhomboid_SP	98..302	CDD:403706
		Rhomboid	617..758	CDD:396315	31/172 (18%)
		MFS	718..>808	CDD:421695	20/97 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820