Protein Alignment rho-4 and Rhbdl3

DIOPT Version :9

• Sequence 1: NP_525084.1
• Gene: rho-4 / 32109
• FlyBaseID: FBgn0030318
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_001099289.1
• Gene: Rhbdl3 / 287556
• RGDID: 1311901
• Length: 404
• Species: Rattus norvegicus
• Alignment Length: 412
• Identity: 113/412 - (27%)
• Similarity: 196/412 - (47%)
• Gaps: 65/412 - (15%)

  Fly    37 ERRSP-PSRPQTLRQDTIDMEEIPLNQTNSQEPEDRRKMHEIFDKHDSDRDGLINTHELKELISD 100
            |..|| |:.......:.|:..|....:.....|||..|:  :|:|.|....|.|:|.:.:.|: :
  Rat     3 EHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKV--LFEKFDPGSTGYISTGKFRSLL-E 64

  Fly   101 GYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAM-------SLRHKWMVRN-------------- 144
            .:...:..:..:.:|..:|...||.:.:::|..:       |.|...:..|
  Rat    65 SHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGL 129

  Fly   145 -MLTRYCRYVVPPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFL----------VDVI 198
             :..|..|:|.....|.|.|..  .|....:.||||..|:..:::|:.:||          :.|.
  Rat   130 SLSQRLIRHVAYETLPREIDRK--WYYDSYTCCPPPWFMITITLLEVALFLYNGVLLDQFVLQVT 192

  Fly   199 HFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALE 263
            |    |.|           .....:|:|..|.:.||:|:|:|:|.|:..|.:|:.:|:.:|:.||
  Rat   193 H----PRY-----------LKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLE 242

  Fly   264 LVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEM--EYAIVQ 326
            :||...|:||||:|||:|||:..|:......:.|:|||||||::||:|.|:||:|.|  ::.:::
  Rat   243 MVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLR 307

  Fly   327 LLAFLVFCFTDLGTSVYRHLTDQHDQI-------GYVAHLSGAVAGLLVGIGVLRNLEVRRWERI 384
            :...|:....:.|.:|:...   |...       .:||||.|...|:.:|:.||||.|.|..::.
  Rat   308 MAVALICMSMEFGRAVWLRF---HPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQS 369

  Fly   385 LWWVAVIVYFALMTTGIIIHVF 406
            |||:.|.:|...:...:..::|
  Rat   370 LWWIFVTMYTIFVLFAVFWNIF 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	35/171 (20%)
		EFh	73..134	CDD:238008	13/60 (22%)
		Rhomboid	226..374	CDD:396315	57/156 (37%)
Rhbdl3	NP_001099289.1	EF-hand_7	36..100	CDD:404394	15/66 (23%)
		Rhomboid	205..359	CDD:396315	57/156 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	142	1.000	Domainoid score	I4562
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.880