Protein Alignment rho-4 and Rhbdl3

DIOPT Version :9

• Sequence 1: NP_525084.1
• Gene: rho-4 / 32109
• FlyBaseID: FBgn0030318
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: XP_006533389.1
• Gene: Rhbdl3 / 246104
• MGIID: 2179276
• Length: 433
• Species: Mus musculus
• Alignment Length: 278
• Identity: 71/278 - (25%)
• Similarity: 123/278 - (44%)
• Gaps: 53/278 - (19%)

  Fly    37 ERRSP-PSRPQTLRQDTIDMEEIPLNQTNSQEPEDRRKMHEIFDKHDSDRDGLINTHELKELISD 100
            |..|| |:.......:.|:..|....:.....|||..|:  :|:|.|....|.|:|.:.:.|: :
Mouse     3 EHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKV--LFEKFDPGSTGYISTGKFRSLL-E 64

  Fly   101 GYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAM-------SLRHKWMVRN-------------- 144
            .:...:..:..:.:|..:|...||.:.:::|..:       |.|...:..|
Mouse    65 SHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGL 129

  Fly   145 -MLTRYCRYVVPPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFL----------VDVI 198
             :..|..|:|.....|.|.|..  .|....:.||||..|:..:::|:.:||          :.|.
Mouse   130 SLSQRLIRHVAYETLPREIDRK--WYYDSYTCCPPPWFMITITLLEVALFLYNGVLLDQFVLQVT 192

  Fly   199 HFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALE 263
            |    |.|           .....:|:|..|.:.||:|:|:|:|.|:..|.:|:.:|:.:|:.||
Mouse   193 H----PRY-----------LKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLE 242

  Fly   264 LVHHWWRVGLVYLAGVLA 281
            :||...|:||||:|||:|
Mouse   243 MVHGATRIGLVYVAGVVA 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	35/171 (20%)
		EFh	73..134	CDD:238008	13/60 (22%)
		Rhomboid	226..374	CDD:396315	26/56 (46%)
Rhbdl3	XP_006533389.1	EF-hand_7	36..100	CDD:372618	15/66 (23%)
		Rhomboid	207..>260	CDD:389796	24/52 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	142	1.000	Domainoid score	I4661
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.880