DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and rhbdl3

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	XP_031750644.1	Gene:	rhbdl3 / 101732375	-ID:	-	Length:	350	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	94/288 - (32%)
Similarity:	154/288 - (53%)	Gaps:	32/288 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 LRHKWMVR----NMLTRYCRYVVPPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMF--- 193
            ||:|.::.    ::..|:.|::.....|.|.|. ...|:.... ||||..::..:|:|:..|
Frog    59 LRNKALLEESGLSLTQRFIRHMAYETLPREIDR-KWFYDNYTG-CPPPWFIITVTIVEVAAFVYY 121

  Fly   194 --LVDVIHFQ-DDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQ 255
              ::|....| ..|.|      ..:.|    .:|:|..|.:.||::||||:|.||.||.:|:.:|
Frog   122 GLVLDRFVLQATHPRY------LRNNP----LVYHPQVRVQAWRYLSYMFMHAGIEHLGVNVALQ 176

  Fly   256 IFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEM 320
            :.:|:.||:||...|:..||:||:||||:..|:........|||.|||||::||:|.|:||:|.|
Frog   177 LLVGVPLEMVHGAVRISFVYIAGILAGSLAVSVADTSAPAVGASAGVYALLSAHLANIVMNWSGM 241

  Fly   321 EYAIVQL-LAFLVFCFT-DLGTSVYRHLTDQ------HDQIGYVAHLSGAVAGLLVGIGVLRNLE 377
            :.....| .||.:.|.: :.|.:|:..|...      |.  .:||||.|.:.|:.:|:..|||.|
Frog   242 KCQFKLLRTAFALICMSFEFGRAVWLRLYPSAYAPCPHP--SFVAHLGGVLVGITLGVITLRNYE 304

  Fly   378 VRRWERILWWVAVIVYFALMTTGIIIHV 405
            .|..::.||||.:.:|...:|..::.::
Frog   305 QRLRDQSLWWVFLAIYVLFVTFAVLWNI 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	16/69 (23%)
		EFh	73..134	CDD:238008
		Rhomboid	226..374	CDD:396315	61/155 (39%)
rhbdl3	XP_031750644.1	Rhomboid	152..301	CDD:396315	59/150 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010