DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-4 and rhbdf1

DIOPT Version :9

Sequence 1:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	XP_004917997.1	Gene:	rhbdf1 / 100494777	XenbaseID:	XB-GENE-6083739	Length:	892	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	71/413 - (17%)
Similarity:	148/413 - (35%)	Gaps:	119/413 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LRQDTIDMEEIPLNQTNSQEPEDRRKMHEIFDKHDSDRDGLINTHE------------------L 94
            :|||....:.|.:|:       |:.|......:  :|:.|.|.|.|                  .
Frog   515 MRQDQDVYKFIKINR-------DKEKNSACCVR--NDKSGCIQTSEEECSSTLAVWVKWPTHSST 570

  Fly    95 KELI------SDGYCRDIPAYIA-----------DQILK--RSDQDNDGHLDFEEFYAMS----- 135
            .||.      |...|...|.:.|           |.|.|  ...:::|||  |.....|.
Frog   571 PELANKSARHSGSVCHQDPRFCAEPASVTPHEWPDDITKWPVCTKNSDGH--FPNHLHMDCVITG 633

  Fly   136 ----LRHKWMVRNMLTRYCRYVVPPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFLVD 196
                :..|.........||.::            .|.:.::.::|..  ...:..:..::.||
Frog   634 RPCCIGTKGRCEITSREYCDFM------------KGYFHEEATLCSQ--VHCMDDVCGLLPFL-- 682

  Fly   197 VIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIA 261
                  ||.:.|::                   |..|   ..:|:|.|::|.::::..|:.:...
Frog   683 ------DPEFPDQV-------------------YRLW---LSLFLHAGVLHCLVSVCFQMTILRD 719

  Fly   262 LELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEME---YA 323
            ||.:..|.|:.::|:...:.|::.:::..|.....|.:|..:.::......:..::..:.   .|
Frog   720 LEKLAGWHRISIIYILSGITGNLTSAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRA 784

  Fly   324 IVQLLAFLVFCFTDLGTSVYRHLTDQHDQIGYVAHLSGAVAGLLVGIGVLRNLEVRRWE----RI 384
            ..:|.|.::|.|| .|...:         |...||.:|.|:|..:....|..:...:::    |.
Frog   785 FFKLFAVVIFLFT-FGLLPW---------IDNFAHFAGFVSGFFLSFAFLPYISFGKFDMYRKRC 839

  Fly   385 LWWVAVIVYFALMTTGIIIHVFV 407
            ...:.::::|.|. :|:::..:|
Frog   840 QIIIFLLIFFGLF-SGLVVLFYV 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	30/185 (16%)
		EFh	73..134	CDD:238008	19/97 (20%)
		Rhomboid	226..374	CDD:396315	29/150 (19%)
rhbdf1	XP_004917997.1	Rhomboid_SP	127..345	CDD:372211
rhbdf1	XP_004917997.1	Rhomboid	687..827	CDD:366759	31/171 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010