DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1561 and CG6834

DIOPT Version :9

Sequence 1:	NP_996412.1	Gene:	CG1561 / 32108	FlyBaseID:	FBgn0030317	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	120/494 - (24%)
Similarity:	195/494 - (39%)	Gaps:	111/494 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 APAEQVDQKEAEPDPHEDTEDERNGEVNREH--PDRMESPVEQQEDTAKPD-------EDLPNEQ 227
            |.|..::||:|..:....:..:..|......  |.::..|:|  :....|:       |:|....
  Fly    15 ASAGDLNQKKASINISGSSNAKIKGSTTTADTPPPQLPCPIE--KSNLGPEWLNQTQFEELLAAH 77

  Fly   228 VTQFLRQLVSQLWPELGANPELRLERASAKGDNYLGVVWRLQ---AASDSKRSLV---VKLPPQN 286
            |.||.:.:..|:.|            |.|.|:||..::.|:.   ..:|....||   :|: |.|
  Fly    78 VDQFSKIVGFQVKP------------AMAPGENYATLMLRISIDVELTDKSTKLVCFMLKV-PHN 129

  Fly   287 RVRRKQFFARPCFLR-ETAAYEVFLPLTALIQDKWKIIG-DDRFRQHALCFGTRQDEPN--ECIV 347
            ..:.:|..|...|.. |...|...||   .:::.:|..| |..|...|....:.: ||.  ..::
  Fly   130 VPQMEQMLAMANFFNSENKVYSDILP---KLEELYKAKGLDITFAPKAFKLDSVK-EPKLANTVL 190

  Fly   348 LEDLSCAGFSLHNRFLDLSVEHVRRVMLTYAKLHAISLAGKRQLPEKMQQLQQLVDIFEQRRDDH 412
            :.|||..||...||...|::|..:..:...|:.||.|              ...|.:.....|..
  Fly   191 MSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAAS--------------SMNVQVNGPYEDQF 241

  Fly   413 ALGV----------YFENLKESALSALLA-----PADDAYRVRLEAYFARGSYFELLLPLVSGFN 462
            ..||          ::|.:..|..:||:|     ...:.:|.:||..|.     ::.|.......
  Fly   242 VNGVMGGNKEVLMAFYEGMVASFRTALMANLKNFKNGEEFREKLEKAFV-----QIFLDFEHLMT 301

  Fly   463 CEP--FAVICHGDCWNNNILYKSTERGELEDVRLIDWQLMRYASPVTDLAYFLFTCTSRRFRQRH 525
            .:|  |.|:.|||||.||:|:|...:||::|:..:|:|..:|.||..||.|.:.|.....::..:
  Fly   302 ADPDEFNVLNHGDCWMNNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDY 366

  Fly   526 LENMLEDYYEELGLQLIRLGERVEQLFPRPAFDE---------QVATKAAVGLLLAMMVLPIVTM 581
            .|..:..|:|:|...|..||...:|    |:..|         ..|...::|      |||||.:
  Fly   367 FEYFIRHYHEQLTQHLDLLGFTGKQ----PSLRELHMLMYKHGSWAVFPSIG------VLPIVLL 421

  Fly   582 QGQDVPDLQAISERIEAGATTDLHGAGFLG-AGNEATFK 619
            .    |:..|..|             .||| :.:.|.||
  Fly   422 D----PNESATFE-------------NFLGDSESSAKFK 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1561	NP_996412.1	EcKinase	257..546	CDD:281023	81/315 (26%)
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	81/315 (26%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459863
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840